497853-07-3

Upstream product

• 130219-46-4 S-<(benzyloxy)carbonyl>-4-aminobenzenethiol 
• 313736-34-4 7-{4-[2-(butoxy)ethoxy]phenyl}-1-isobutyl-2,3-dihydro-1H-1-benzazepine-4-carboxylic acid 
• 1193-02-8 4-aminotiophenol 
• 497855-77-3 (1-isobutyl-1H-imidazol-2-yl)methanol 
• 497855-76-2 1-isobutyl-1H-imidazole-2-carbaldehyde 
• 597583-16-9 7-[4-(2-butoxy-ethoxy)-phenyl]-1-isobutyl-2,3-dihydro-1H-benzo[b]azepine-4-carbonyl chloride 

Relevant academic research and scientific papers

Orally active CCR5 antagonists as anti-HIV-1 agents. Part 3: Synthesis and biological activities of 1-benzazepine derivatives containing a sulfoxide moiety

In order to develop orally active CCR5 antagonists, 1-propyl- or 1-isobutyl-1-benzazepine derivatives containing a sulfoxide moiety have been designed, synthesized, and evaluated for their biological activities. Sulfoxide compounds containing a 2-pyridyl

BENZAZEPINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE

The present invention provides a novel benzazepine derivative represented by formula : wherein, R1 is a 5- or 6-membered aromatic ring, R2 is lower alkyl group, etc., Y is an optionally substituted imino group, ring A and ring B are independently an optionally substituted aromatic ring, W is formula -W1-X2-W2- (W1 and W2 are independently S(O)m1 (m1 is 0, 1 or 2), etc., and X2 is an optionally substituted alkylene groupetc. ), a preparation method and use thereof.