497853-80-2

Basic information

• Product Name: Benzenamine, 4-[[(1-ethyl-1H-imidazol-2-yl)methyl]thio]-
• CAS NO: 497853-80-2
• Molecular Formula: C12H15N3S
• Molecular Weight: 233.337
• Mol File: 497853-80-2.mol

Chemical Properties

• CAS DataBase Reference: Benzenamine, 4-[[(1-ethyl-1H-imidazol-2-yl)methyl]thio]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 4-[[(1-ethyl-1H-imidazol-2-yl)methyl]thio]-(497853-80-2)
• EPA Substance Registry System: Benzenamine, 4-[[(1-ethyl-1H-imidazol-2-yl)methyl]thio]-(497853-80-2)

Safety Data

• Hazardous Substances Data: 497853-80-2(Hazardous Substances Data)

Upstream product

• 63634-44-6 1-ethyl-2-(hydroxymethyl)-1H-imidazole 
• 1193-02-8 4-aminotiophenol 
• 111851-98-0 1-ethyl-2-formylimidazole 

Downstream Products

• 497852-90-1 7-{4-[2-(butoxy)ethoxy]phenyl}-1-isobutyl-N-({4-[(1-ethyl-1H-imidazol-2-yl)methyl]sulfanyl}phenyl)-2,3-dihydro-1H-1-benzazepine-4-carboxamide 
• 497852-91-2 7-[4-(2-butoxyethoxy)phenyl]-N-[4-[[(1-ethylimidazol-2-yl)methyl]sulfinyl]phenyl]-1-isobutyl-2,3-dihydro-1-benzazepine-4-carboxamide 

Relevant articles and documents

Orally active CCR5 antagonists as anti-HIV-1 agents. Part 3: Synthesis and biological activities of 1-benzazepine derivatives containing a sulfoxide moiety

In order to develop orally active CCR5 antagonists, 1-propyl- or 1-isobutyl-1-benzazepine derivatives containing a sulfoxide moiety have been designed, synthesized, and evaluated for their biological activities. Sulfoxide compounds containing a 2-pyridyl

BENZAZEPINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE

The present invention provides a novel benzazepine derivative represented by formula : wherein, R1 is a 5- or 6-membered aromatic ring, R2 is lower alkyl group, etc., Y is an optionally substituted imino group, ring A and ring B are independently an optionally substituted aromatic ring, W is formula -W1-X2-W2- (W1 and W2 are independently S(O)m1 (m1 is 0, 1 or 2), etc., and X2 is an optionally substituted alkylene groupetc. ), a preparation method and use thereof.