497933-10-5Relevant academic research and scientific papers
An efficient synthesis of (E)-α,β-unsaturated ketones and esters with total stereoselectivity by using chromium dichloride
Concellón, José M.,Rodríguez-Solla, Humberto,Méjica, Carmen
, p. 3292 - 3300 (2007/10/03)
(E)-α,β-Unsaturated ketones 1 or esters 2 can be obtained with complete stereoselectivity by reaction of different 2-chloro-3-hydroxy ketones 3 or esters 4 and CrCl2. A comparative study of the results of synthesis of ketones 1 with CrCl2 or samarium is performed. A mechanism to explain both β-elimination reactions has been proposed.
Synthesis of (E)-α,β-unsaturated ketones with total or high diastereoselectivity by using samarium diiodide or triiodide
Concellón, José M.,Huerta, Mónica
, p. 1931 - 1934 (2007/10/03)
(E)-α,β-Unsaturated ketones are obtained by reaction of α-chloro-β-hydroxy ketones with samarium diiodide or with samarium triiodide with total or high diastereoselectivity and in good yield.
Preparation of (Z)-α-chloro-α,β-unsaturated ketones with total or high diastereoselectivity
Concellón, José M,Huerta, Mónica
, p. 7775 - 7780 (2007/10/03)
(Z)-α-Chloroenones are obtained by reaction of α-chloro-β-hydroxyketones with acetic anhydride, pyridine and 4-dimethylaminopyridine with total or high diastereoselectivity and in high yield.
