497953-24-9Relevant academic research and scientific papers
Biocatalysis at Work: Applications in the Development of Sagopilone
Gottfried, Kathrin,Klar, Ulrich,Platzek, Johannes,Zorn, Ludwig
, p. 1240 - 1248 (2015)
For the antitumour agent sagopilone, an epothilone analogue, a large-scale synthesis was developed to synthesise the active pharmaceutical ingredient for clinical trials, exploring enzymatic and microbial methods to produce chiral building blocks on a mul
Protected 3,-5-dihydroxy-2,2-dimethyl-valeronitriles for the synthesis of epothilones and epothilone derivatives and process for the production
-
, (2008/06/13)
The invention relates to 3,5-dihydroxy-2,2-dimethyl-valeronitriles for the synthesis of epothilones and epothilone derivatives and process for the production of these new intermediate products in the synthesis and the use for the production of epothilones
