497959-33-8 Usage
General Description
2-Bromo-4-(trifluoromethyl)benzyl alcohol is a chemical compound with the molecular formula C8H6BrF3O. It is a white to off-white solid that is commonly used as a building block in organic synthesis. The compound is known for its wide range of applications in pharmaceuticals, agrochemicals, and materials science. It is also used as an intermediate in the synthesis of various biologically active compounds. Additionally, the compound is found to possess antimicrobial and antifungal properties, making it useful in the development of new pharmaceuticals and pesticides.
Check Digit Verification of cas no
The CAS Registry Mumber 497959-33-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,9,7,9,5 and 9 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 497959-33:
(8*4)+(7*9)+(6*7)+(5*9)+(4*5)+(3*9)+(2*3)+(1*3)=238
238 % 10 = 8
So 497959-33-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H6BrF3O/c9-7-3-6(8(10,11)12)2-1-5(7)4-13/h1-3,13H,4H2
497959-33-8Relevant articles and documents
tBuOK-Promoted Cyclization of Imines with Aryl Halides
Li, Ya-Wei,Zheng, Hong-Xing,Yang, Bo,Shan, Xiang-Huan,Qu, Jian-Ping,Kang, Yan-Biao
supporting information, p. 4553 - 4556 (2020/06/08)
A transition-metal-free indole synthesis using radical coupling of 2-halotoluenes and imines via the later-stage C-N bond construction was reported for the first time. It includes an aminyl radical generation by C-H cleaving addition of 2-halotoluenes to imines via the carbanion radical relay and an intramolecular coupling of aryl halides with aminyl radicals. One standard condition can be used for all halides including F, Cl, Br, and I. No extra oxidant or transition metal is required.
