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1-(2-Benzyloxy-ethyl)-piperazine, with the chemical formula C14H24N2O and a molecular weight of 236.35 g/mol, is an organic compound belonging to the class of piperazine derivatives. It is a piperazine derivative that is functionalized with a benzyl group and an ethoxy moiety, known for its potential applications in pharmaceuticals, organic synthesis, and industrial applications.

4981-85-5

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4981-85-5 Usage

Uses

Used in Pharmaceutical Industry:
1-(2-Benzyloxy-ethyl)-piperazine is used as a building block for the synthesis of various pharmaceuticals due to its unique chemical structure and functional groups. Its versatility in chemical reactions allows for the creation of a wide range of drug candidates.
Used in Organic Synthesis:
1-(2-Benzyloxy-ethyl)-piperazine is used as a key intermediate in the synthesis of complex organic compounds. Its presence in the molecule can influence the reactivity and selectivity of the reactions, making it a valuable component in organic chemistry.
Used in Anticancer Research:
1-(2-Benzyloxy-ethyl)-piperazine is used as a potential anticancer agent in preliminary studies. Its ability to interact with biological targets and modulate cellular processes makes it a promising candidate for further research and development in oncology.
Used in Central Nervous System Depressant Research:
1-(2-Benzyloxy-ethyl)-piperazine is studied for its potential as a central nervous system depressant. Its effects on neurotransmitter systems and neuronal activity could lead to the development of new therapeutic agents for the treatment of anxiety, insomnia, and other related conditions.
Used in Metalworking Industry:
1-(2-Benzyloxy-ethyl)-piperazine has been studied for its potential use as a corrosion inhibitor in metalworking applications. Its ability to form protective layers on metal surfaces and reduce corrosion rates could improve the durability and performance of metal components in various industrial settings.

Check Digit Verification of cas no

The CAS Registry Mumber 4981-85-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,9,8 and 1 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 4981-85:
(6*4)+(5*9)+(4*8)+(3*1)+(2*8)+(1*5)=125
125 % 10 = 5
So 4981-85-5 is a valid CAS Registry Number.
InChI:InChI=1/C13H20N2O/c1-2-4-13(5-3-1)12-16-11-10-15-8-6-14-7-9-15/h1-5,14H,6-12H2

4981-85-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-phenylmethoxyethyl)piperazine

1.2 Other means of identification

Product number -
Other names N-(2-Benzyloxyethyl)piperazin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:4981-85-5 SDS

4981-85-5Relevant academic research and scientific papers

AROMATIC HETEROCYCLIC COMPOUND WITH KINASE INHIBITORY ACTIVITY

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Paragraph 0207-0209, (2021/07/29)

Provided are a JAK kinase inhibitor, preparation and use thereof. In particular, provided is a compound of Formula I, wherein each group is as described in the specification. The compound has an excellent JAK inhibitory activity, and therefore can be used to prepare pharmaceutical compositions for the treatment of cancer and other diseases related to JAK activity.

Synthesis and preliminary pharmacological evaluation of 4′-arylalkyl analogues of clozapine. II. Effect of the nature and length of the linker

Capuano, Ben,Crosby, Ian T.,Lloyd, Edward J.,Podloucka, Anna,Taylor, David A.

, p. 875 - 886 (2007/10/03)

We report the synthesis of a second generation of tricyclic analogues of clozapine, investigating the length and nature of the chain between an ionizable nitrogen atom at physiological pH and the introduced aryl moiety. The chemistry, structural characterization, and pharmacological evaluation of this series of 4′-arylalkyl analogues of clozapine are described. Preliminary findings on the effects on activity of the nature and length of the linker, degree of unsaturation, and type of aryl moiety on blockade of dopamine D4 and serotonin 5-HT2A receptors are discussed and animal behavioural data for key compounds presented.

Synthesis and psychoanaleptic properties of new compounds structurally related to diphenhydramine

Buzas,Champagnac,Dehnel,Lavielle,Pommier

, p. 149 - 153 (2007/10/02)

A new series of benzhydryloxyalkylpiperazines carrying a trivalent function has been synthesized and studied for its effects on the central nervous system. Most of the compounds exhibit unexpected nonamphetaminic psychoanaleptic properties. The structure-

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