4981-85-5

Basic information

• Product Name: 1-(2-BENZYLOXY-ETHYL)-PIPERAZINE
• Synonyms: 1-(2-BENZYLOXY-ETHYL)-PIPERAZINE;CHEMPACIFIC 41239;1-(2-BENZYLOXY-ETHYL)-PIPERAZINE HYDROCHLORIDE;1-(2-BENZYLOXY-ETHYL)-PIPERAZINE >98%;1-[2-(PhenylMethoxy)ethyl]piperazine 2HCl;Piperazine,1-[2-(phenylmethoxy)ethyl]- 4981-85-5;1-(2-phenylmethoxyethyl)piperazine
• CAS NO: 4981-85-5
• Molecular Formula: C₁₃H₂₀N₂O
• Molecular Weight: 220.31
• Product Categories: Piperaizine;piperazines
• Mol File: 4981-85-5.mol
• Article Data: 3

Chemical Properties

• Melting Point: 30-34 °C
• Boiling Point: 326.2°Cat760mmHg
• Flash Point: 151.1°C
• Appearance: /
• Density: 1.026g/cm³
• Vapor Pressure: 0.00022mmHg at 25°C
• Refractive Index: 1.522
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 9.14±0.10(Predicted)
• CAS DataBase Reference: 1-(2-BENZYLOXY-ETHYL)-PIPERAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-BENZYLOXY-ETHYL)-PIPERAZINE(4981-85-5)
• EPA Substance Registry System: 1-(2-BENZYLOXY-ETHYL)-PIPERAZINE(4981-85-5)

Safety Data

• Hazard Codes: T
• Statements: 25-36
• Safety Statements: 26-45
• Hazardous Substances Data: 4981-85-5(Hazardous Substances Data)

Usage

General Description

1-(2-Benzyloxy-ethyl)-piperazine is a chemical compound with the formula C14H24N2O and a molecular weight of 236.35 g/mol. It is an organic compound that belongs to the class of piperazine derivatives, which are widely used in pharmaceutical and industrial applications. 1-(2-BENZYLOXY-ETHYL)-PIPERAZINE is a piperazine derivative functionalized with a benzyl group and an ethoxy moiety. It is commonly used as a building block in the synthesis of various pharmaceuticals and organic compounds, and it has shown potential as an anticancer agent and a central nervous system depressant in preliminary studies. Additionally, it has been studied for its potential use as a corrosion inhibitor in metalworking applications.

InChI:InChI=1/C13H20N2O/c1-2-4-13(5-3-1)12-16-11-10-15-8-6-14-7-9-15/h1-5,14H,6-12H2

Upstream product

• 110-85-0 piperazine 
• 1462-37-9 bromoethyl-2-benzyl ether 
• 17229-17-3 benzyl 2-chloroethyl ether 

Downstream Products

• 302962-49-8 dasatanib 
• 1245157-61-2 2-(6-(4-(2-benzoxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-formic acid 
• 1245157-70-3 C₂₉H₃₂ClN₇O₂S 

Relevant articles and documents

AROMATIC HETEROCYCLIC COMPOUND WITH KINASE INHIBITORY ACTIVITY

Provided are a JAK kinase inhibitor, preparation and use thereof. In particular, provided is a compound of Formula I, wherein each group is as described in the specification. The compound has an excellent JAK inhibitory activity, and therefore can be used to prepare pharmaceutical compositions for the treatment of cancer and other diseases related to JAK activity.

Synthesis and psychoanaleptic properties of new compounds structurally related to diphenhydramine

A new series of benzhydryloxyalkylpiperazines carrying a trivalent function has been synthesized and studied for its effects on the central nervous system. Most of the compounds exhibit unexpected nonamphetaminic psychoanaleptic properties. The structure-