1245157-61-2

Basic information

• Product Name: 2-(6-(4-(2-benzoxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-formic acid
• Synonyms: 2-(6-(4-(2-benzoxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-formic acid
• CAS NO: 1245157-61-2
• Molecular Weight: 454.553
• Mol File: 1245157-61-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(6-(4-(2-benzoxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-formic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(6-(4-(2-benzoxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-formic acid(1245157-61-2)
• EPA Substance Registry System: 2-(6-(4-(2-benzoxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-formic acid(1245157-61-2)

Safety Data

• Hazardous Substances Data: 1245157-61-2(Hazardous Substances Data)

Upstream product

• 1245157-45-2 methyl 2-(6-bromo-2-methylpyrimidin-4-ylamino)thiazole-5-formate 
• 4981-85-5 1-[2-(benzyloxy)ethyl]piperazine 
• 1161763-15-0 4-amino-6-bromo-2-methylpyrimidine 
• 1245157-52-1 methyl 2-(6-(4-(2-benzoxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-formate 

Downstream Products

• 1245157-70-3 C₂₉H₃₂ClN₇O₂S 
• 302962-49-8 dasatanib 

Relevant articles and documents

SYNTHESIS PROCESS OF DASATINIB AND INTERMEDIATE THEREOF

Synthesis process of dasatinib is disclosed, which includes the step of reacting the compound of formula I with that of formula II to obtain the compound of formula III. Also disclosed is the compound of formula III which is used as an intermediate for synthesizing dasatinib. The substituents of R1, R2, R3 or R4 in formulae I, II or III are defined as in the description.