49818-39-5

Upstream product

• 67-56-1 methanol 
• 39595-88-5 2-(2-(benzyloxy)-3-methoxyphenyl)acetic acid 

Downstream Products

• 1431564-22-5 methyl 2-(2-((3,4-dimethoxybenzyl)oxy)-3-methoxyphenyl)acetate 
• 1431564-23-6 methyl 2-diazo-2-(2-((3,4-dimethoxybenzyl)oxy)-3-methoxyphenyl)acetate 
• 1431564-24-7 (2R,3S)-methyl 2-(3,4-dimethoxyphenyl)-7-methoxy-2,3-dihydrobenzofuran-3-carboxylate 
• 628331-49-7 benzyl 2-(2-hydroxy-3-methoxyphenyl)acetate 

Relevant academic research and scientific papers

Sequential C-H functionalization reactions for the enantioselective synthesis of highly functionalized 2,3-dihydrobenzofurans

The enantioselective synthesis of 2,3-dihydrobenzofurans was achieved by using two sequential C-H functionalization reactions, a rhodium-catalyzed enantioselective intermolecular C-H insertion followed by a palladium-catalyzed C-H activation/C-O cyclization. Further diversification of the 2,3-dihydrobenzofuran structures was possible by a subsequent palladium-catalyzed intermolecular Heck-type sp2 C-H functionalization.