49820-06-6

Basic information

• Product Name: 4,6-DIMETHYL-1H-INDOLE-2,3-DIONE
• Synonyms: 4,6-DiMethylisatin;4,6-dimethylindoline-2,3-dione
• CAS NO: 49820-06-6
• Molecular Formula: C₁₀H₉NO₂
• Molecular Weight: 175.18
• Mol File: 49820-06-6.mol

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.25g/cm³
• Refractive Index: 1.586
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4,6-DIMETHYL-1H-INDOLE-2,3-DIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-DIMETHYL-1H-INDOLE-2,3-DIONE(49820-06-6)
• EPA Substance Registry System: 4,6-DIMETHYL-1H-INDOLE-2,3-DIONE(49820-06-6)

Safety Data

• Hazardous Substances Data: 49820-06-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4,6-DIMETHYL-1H-INDOLE-2,3-DIONE is used as a key intermediate in the synthesis of various pharmaceuticals for its versatile chemical properties and potential therapeutic applications.
Used in Antiviral Applications:
4,6-DIMETHYL-1H-INDOLE-2,3-DIONE is used as an antiviral agent for its ability to inhibit viral replication and protect against viral infections.
Used in Antifungal Applications:
4,6-DIMETHYL-1H-INDOLE-2,3-DIONE is used as an antifungal agent to combat fungal infections and prevent their progression.
Used in Antibacterial Applications:
4,6-DIMETHYL-1H-INDOLE-2,3-DIONE is used as an antibacterial agent to target and eliminate bacterial pathogens, contributing to the treatment of bacterial diseases.
Used in Neurodegenerative Disease Treatment:
4,6-DIMETHYL-1H-INDOLE-2,3-DIONE is used as a monoamine oxidase (MAO) inhibitor for its potential to mitigate neurodegenerative diseases such as Parkinson's and Alzheimer's by regulating monoamine levels in the brain.
Used in Anticancer Applications:
4,6-DIMETHYL-1H-INDOLE-2,3-DIONE is used as an anticancer agent for its potential to inhibit cancer cell growth and induce apoptosis, making it a valuable compound in the development of novel therapeutic drugs for cancer treatment.

InChI:InChI=1/C10H9NO2/c1-5-3-6(2)8-7(4-5)11-10(13)9(8)12/h3-4H,1-2H3,(H,11,12,13)

Upstream product

• 266348-65-6 3-benzyl-3-hydroxy-5,7-dimethyl-1H-quinoline-2,4-dione 
• 266348-67-8 3-hydroxy-5,7-dimethyl-3-phenyl-1H-quinoline-2,4-dione 

Downstream Products

• 1306909-36-3 C₁₇H₁₅NO₂ 
• 1246250-87-2 2-(3,5-dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethylquinazolin-4(3H)-one 
• 875241-52-4 2-amino-4,6-dimethyl benzamide 
• 1424209-50-6 8,10-dimethyl-4,5,6,7-tetraphenylazepino[3,2,1-hi]indole-1,2-dione 
• 109082-15-7 dimethyl 2,2'-(oxalyldiimino)bis(4,6-dimethylphenylglyoxylate) 
• 107642-75-1 4-methoxy-3,4',5,6'-tetramethyl-2'-(4-toluenesulphonamino)diphenyl ketone 
• 107642-74-0 2,4-dimethyl-6-(4-methylphenylsulfonamido)benzoic acid 
• 107642-76-2 2'-amino-4-methoxy-3,4',5,6'-tetramethyldiphenyl ketone 
• 90321-33-8 2-amino-4,6-dimethyl-benzoic acid 

Relevant articles and documents

Synthesis of novel 3-acyloxy-1,3-dihydro-2H-indol-2-ones and isomeric 4- acyl-1,4-dihydro-3,1-benzoxazin-2-ones: Double rearrangement of 3- hydroxyquinoline-2,4(1H,3H)-diones

Substituted 3-hydroxyquinoline-2,4(1H,3H)-diones 3 were transformed into 3-acyloxy-1,3-dihydro-2H-indol-2-ones 4 and isomeric 4-acyl-1,4-dihydro-3,1- benzoxazin-2-ones 5. The influence of the substituents and the reaction conditions on the course of the r