49840-84-8Relevant academic research and scientific papers
Synthesis of substituted acetylenes, aryl-alkyl ethers, 2-alkene-4-ynoates and nitriles using heterogeneous mesoporous Pd-MCM-48 as reusable catalyst
Banerjee, Subhash,Khatri, Hari,Balasanthiran, Vagulejan,Koodali, Ranjit T.,Sereda, Grigoriy
, p. 5717 - 5724 (2011)
Pd-MCM-48 has been employed as a heterogeneous catalyst for the synthesis of substituted acetylenes via Sonogashira reactions under copper and amine-free reaction conditions. In addition, the catalyst exhibited excellent regioselectivity for primary alcohols towards C-O coupling leading to formation of alkyl-aryl ethers in high yields. A green procedure for the stereoselective synthesis of 2-alkene-4-ynoates and nitriles from the reactions of vic-(E)-diiodoalkenes with activated alkenes has also been demonstrated using Pd-MCM-48 catalyst. The catalyst was easily recovered from the reaction mixture by filtration and reused for at least six times with minimal loss of activity.
A CONVENIENT STEREOSELECTIVE SYNTHESIS OF CONJUGATED (2Z)-EN-4-YNOIC AND (2Z,4Z)- AND (2Z,4E)-DIENOIC ACID DERIVATIVES FROM PROPIOLIC ACID DERIVATIVES
Lu, Xiyan,Huang, Xiaoling,Ma, Shengming
, p. 2535 - 2538 (2007/10/02)
The palladium-catalysed one-pot sequential reaction of propiolic acid derivatives with lithium halides first, and then with terminal alkynes or alkenes affords conjugated (2Z)-en-4-ynoic and (2Z,4Z)- and (2Z,4E)-dienoic acid derivatives with high stereoselectivity.
