498548-09-7

Upstream product

• 76304-55-7 3-(3-pyridyl)pyrrole 
• 72692-99-0 3-(1H-pyrrol-1-yl)pyridine 
• 1225218-98-3 benzyl (R)-3-pyridin-3-ylpyrrolidine-1-carboxylate 
• 145105-05-1 3-[1-(phenylmethyl)-3-pyrrolidinyl]pyridine 

Downstream Products

• 874218-24-3 tert-butyl 3-(pyridin-3-yl)pyrrolidine-1-carboxylate 
• 150281-71-3 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[3-(3-pyridinyl)-1-pyrrolidinyl]-1,8-naphthyridine-3-carboxylic acid 

Relevant academic research and scientific papers

BENZIMIDAZOLE AND AZA-BENZIMIDAZOLE CARBOXAMIDES

This invention provides compounds of Formula I which are PAFR antagonists: I and the pharmaceutically acceptable salts thereof. The compounds are useful for treating PAF-mediated disorders, and can be used in methods for treating atherosclerosis and preve

BIARYL CARBOXAMIDES

This invention provides compounds of Formula (I) which are PAFR antagonists: Formula (I) and the pharmaceutically acceptable salts thereof. The compounds are useful for treating PAF-mediated disorders, and can be used in methods for treating atherosclerosis and preventing or reducing risk for atherosclerotic disease events. The compounds are also useful for treating or ameliorating pain, e.g. inflammatory pain and/or nociceptive pain, and for treating or ameliorating autoimmune and/or inflammatory diseases, among other conditions.

7-substituted quinolones and naphthyridones as antibacterial agents

7-Substituted quinolones and naphthyridones are described as antibacterial agents as well as a process for their manufacture, compositions therefor, wherein the 7-substituent is a pyrrolidine ring substituted at the 3-position by a substituted aromatic hydrocarbon or a heteroaromatic group.