498554-89-5

Upstream product

• 162792-20-3 (1R,2R,3S,4S,5R)-3,4,5-Tris-benzyloxy-cyclohexane-1,2-diol 
• 498554-88-4 1D-4,5,6-tri-O-benzyl-3-deoxy-1-O-p-methoxybenzyl-myo-inositol 

Downstream Products

• 498554-92-0 Phosphoric acid benzyl ester (R)-2-methoxy-3-octadecyloxy-propyl ester (1R,2R,3S,4R,6R)-2,3,4-tris-benzyloxy-6-methoxy-cyclohexyl ester 
• 701976-54-7 phosphoric acid 2-methoxy-3-octadecyloxy-propyl ester 2,3,4-trihydroxy-6-methoxy-cyclohexyl ester 
• 498555-01-4 Carbonic acid (R)-2-methoxy-3-octadecyloxy-propyl ester (1R,2R,3S,4R,6R)-2,3,4-tris-benzyloxy-6-methoxy-cyclohexyl ester 

Relevant academic research and scientific papers

Novel PI analogues selectively block activation of the pro-survival serine/threonine kinase Akt

The synthesis from l-quebrachitol of a series of 3-deoxygenated ether lipid-type phosphatidylinositol (PI) analogues is reported, that selectively block activation of Akt and downstream substrates without affecting activation of the upstream kinase, PDK-1