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Proxymetacaine, also known as proxymetacaine hydrochloride, is a synthetic derivative of the ester class of local anesthetics. It is a crystalline solid that is commonly used as a topical anesthetic, particularly in ophthalmic applications. Proxymetacaine works by blocking nerve conduction, providing temporary pain relief and anesthesia to the treated area.

499-67-2

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499-67-2 Usage

Uses

Used in Ophthalmology:
Proxymetacaine is used as a topical anesthetic for ophthalmic procedures, such as eye examinations and minor eye surgeries. It is applied directly to the surface of the eye to provide rapid and effective pain relief, allowing for a more comfortable and less stressful experience for the patient.
Proxymetacaine is also used as a diagnostic tool in ophthalmology, as it can help to determine the presence of corneal abrasions or other eye injuries by causing a stinging sensation upon contact with the affected area.
Brand names for proxymetacaine include Alcaine (Alcon), Ophthetic (Allergan), and Paracaine (Optopics). These products are widely used in the medical field, particularly in ophthalmology, to ensure patient comfort during various eye-related procedures.

Check Digit Verification of cas no

The CAS Registry Mumber 499-67-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,9 and 9 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 499-67:
(5*4)+(4*9)+(3*9)+(2*6)+(1*7)=102
102 % 10 = 2
So 499-67-2 is a valid CAS Registry Number.
InChI:InChI=1/C16H26N2O3/c1-4-10-20-15-8-7-13(12-14(15)17)16(19)21-11-9-18(5-2)6-3/h7-8,12H,4-6,9-11,17H2,1-3H3

499-67-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name Proparacaine Hydrochloride

1.2 Other means of identification

Product number -
Other names 2-(diethylamino)ethyl 3-amino-4-propoxybenzoate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:499-67-2 SDS

499-67-2Synthetic route

3-nitro-4-propoxy-benzoic acid-(2-diethylamino-ethyl ester)
736870-51-2

3-nitro-4-propoxy-benzoic acid-(2-diethylamino-ethyl ester)

Proparacain
499-67-2

Proparacain

Conditions
ConditionsYield
With ethanol; platinum Hydrogenation;
3-nitro-4-hydroxybenzoic acid
616-82-0

3-nitro-4-hydroxybenzoic acid

Proparacain
499-67-2

Proparacain

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: K2CO3; xylene / Erwaermen des Reaktionsprodukts mit wss.-aethanol. NaOH
2: isopropyl alcohol
3: platinum; ethanol / Hydrogenation
View Scheme
3-nitro-4-propoxybenzoic acid
35288-44-9

3-nitro-4-propoxybenzoic acid

Proparacain
499-67-2

Proparacain

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: isopropyl alcohol
2: platinum; ethanol / Hydrogenation
View Scheme

499-67-2Downstream Products

499-67-2Relevant academic research and scientific papers

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