499195-41-4

Upstream product

• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 
• 499195-27-6 Acetic acid (1S,2S,3R,5S,6R)-2-acetoxy-3,5-diazido-6-(4-methoxy-benzyloxy)-cyclohexyl ester 
• 499195-32-3 1,3-di-azido-5,6-di-O-benzyl-2-deoxystreptamine 
• 870180-36-2 (1S,2R,3R,4S,6R)-4,6-Diazido-3-(4-methoxy-benzyloxy)-cyclohexane-1,2-diol 
• 236115-61-0 [(1S,2S,3R,4S,6R)-2-acetoxy-4,6-diazido-3-hydroxy-cyclohexyl] acetate 
• 499195-37-8 ((1S,2R,3S,4S,5R)-3,4-Bis-benzyloxy-5-benzyloxycarbonylamino-2-hydroxy-cyclohexyl)-carbamic acid benzyl ester 

Downstream Products

• 499195-45-8 ((1S,4R,5R)-4-Benzyloxy-5-benzyloxycarbonylamino-2-formyl-cyclohex-2-enyl)-carbamic acid benzyl ester 
• 499195-49-2 (3R,4R,6S)-3-Benzyloxy-4,6-bis-benzyloxycarbonylamino-cyclohex-1-enecarboxylic acid 

Relevant academic research and scientific papers

Novel 2,5-dideoxystreptamine derivatives targeting the ribosomal decoding site RNA

The ribosomal decoding site is the target of aminoglycoside antibiotics that specifically recognize an internal loop RNA structure. We synthesized RNA-targeted 2,5-dideoxystreptamine-4-amides in which a sugar moiety in natural aminoglycosides is replaced by heterocycles.