4992-09-0Relevant articles and documents
Pd-Catalyzed Cyclocarbonylation of 2-(2-Bromoaryl)indoles with CO as a C1 Source: Selective Access to 6 H-Isoindolo[2,1-a]indol-6-ones and Indeno[1,2-b]indol-10(5 H)-ones
Guo, Shenghai,Tao, Li,Wang, Fang,Fan, Xuesen
, p. 3090 - 3096 (2016/11/13)
A highly efficient and regioselective synthetic route to 6 H-isoindolo[2,1-a]indol-6-ones and indeno[1,2-b]indol-10(5 H)-ones through the Pd-catalyzed cyclocarbonylation of 2-(2-bromoaryl)indoles under atmospheric CO pressure has been achieved. Notably, the regioselectivity of the reaction was exclusively dependent on the structural characteristics of the indole substrates. With N-unsubstituted indoles as the starting materials, the reaction afforded 6H-isoindolo[2,1-a]indol-6-ones in good-to-excellent yields. On the other hand, with N-substituted indoles as the substrates, the reaction gave indeno[1,2-b]indol-10(5 H)-ones in a highly regioselective manner.
OXIDATION OF 1-BENZOYLPYRROLE AND 1-AROYLINDOLES BY PALLADIUM ACETATE
Itahara, Toshio
, p. 2557 - 2562 (2007/10/02)
Oxidation of 1-benzoylpyrrole and 1-aroylindoles by palladium acetate in acetic acid gave the corresponding ring-closed products and dimerized compounds.
Alkenylation of 1-Acylindoles with Olefins Bearing Electron-withdrawing Substituents and Palladium Acetate
Itahara, Toshio,Ikeda, Mizue,Sakakibara, Tsutomu
, p. 1361 - 1363 (2007/10/02)
The oxidation of 1-(2,6-dichlorobenzoyl)indole with olefins, such as alkyl acrylates and acrylonitrile, and palladium acetate resulted in selective 3-alkenylation of the indole nucleus.Treatment of 1-acyl-3-methylindoles under similar conditions gave the corresponding 2-alkenyl substituted indoles, while the oxidation of 6-oxo-6H-isoindoloindole gave the corresponding 3-alkenyl substituted indoles.