499236-68-9

Basic information

• Product Name: Phenol, 2-cyclopropyl-6-methyl- (9CI)
• Synonyms: Phenol, 2-cyclopropyl-6-methyl- (9CI);2-Cyclopropyl-6-methylphenol
• CAS NO: 499236-68-9
• Molecular Formula: C10H12O
• Molecular Weight: 148.20168
• Product Categories: ALCOHOL
• Mol File: 499236-68-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 186.6±9.0 °C(Predicted)
• Appearance: /
• Density: 1.121±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 10.52±0.35(Predicted)
• CAS DataBase Reference: Phenol, 2-cyclopropyl-6-methyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2-cyclopropyl-6-methyl- (9CI)(499236-68-9)
• EPA Substance Registry System: Phenol, 2-cyclopropyl-6-methyl- (9CI)(499236-68-9)

Safety Data

• Hazardous Substances Data: 499236-68-9(Hazardous Substances Data)

Usage

General Description

Phenol, 2-cyclopropyl-6-methyl- (9CI) is a chemical compound that is a derivative of phenol with a cyclopropyl and methyl group attached to the aromatic ring. It is commonly used in the production of various industrial chemicals, pharmaceuticals, and pesticides. Phenol, 2-cyclopropyl-6-methyl- (9CI) has demonstrated biological activity including antimicrobial and antifungal properties. It is important to handle this chemical with care as it can be irritating to the skin, eyes, and respiratory tract, and can be toxic if ingested or inhaled in large amounts. Proper safety precautions should be taken when working with this compound to minimize the risk of exposure and harm.

Upstream product

• 13319-71-6 2-bromo-6-methylphenol 
• 411235-57-9 cyclopropylboronic acid 
• 854260-75-6 2-(allyloxy)-1-bromo-3-methylbenzene 
• 911817-85-1 2-(1,3-dibromopropyl)-6-methylphenyl acetate 

Relevant articles and documents

Pyridine N-oxidation derivative as well as preparation method and application thereof

The invention relates to a pyridine N-oxidation derivative as well as a preparation method and an application thereof, in particular to a compound shown in a general formula (I), a preparation methodof the compound, pharmaceutical composition containing the compound and an application of the compound as a BRD4 inhibitor in treating related diseases such as cancer, inflammation, chronic liver diseases, diabetes, cardiovascular diseases, AIDS and the like, wherein in the general formula (I), all substituent groups are the same as definitions in the description.

5H-PYRROLO[3,4-￡>]PYRAZIN-7-AMINE DERIVATIVES INHIBITORS OF BETA-SECRETASE

The present invention relates to novel compounds of formula (I) and their pharmaceutical compositions. In addition, the present invention relates to therapeutic methods for the treatment and/or prevention of Aβ-related pathologies such as Downs syndrome, β- amyloid angiopathy such as but not limited to cerebral amyloid angiopathy or hereditary cerebral hemorrhage, disorders associated with cognitive impairment such as but not limited to MCI ("mild cognitive impairment"), Alzheimer Disease, memory loss, attention deficit symptoms associated with Alzheimer disease, neurodegeneration associated with diseases such as Alzheimer disease or dementia including dementia of mixed vascular and degenerative origin, pre-senile dementia, senile dementia and dementia associated with Parkinson's disease, progressive supranuclear palsy or cortical basal degeneration.

PROCESS FOR PRODUCING CYCLOPROPYLPHENOL DERIVATIVE

A method of easily synthesizing a cyclopropylphenol derivative. The method, which is a process for producing a cyclopropylphenol derivative represented by the general formula (10): [wherein R1, R2, R3, and R4 each independently is hydrogen, etc.; Z is hydrogen, etc.; and Y1, Y2, and Y3 each independently is hydrogen, etc.], comprises reacting a compound represented by the general formula (7): [wherein the symbols have the same meanings as defined above; X is halogeno; and V is hydrogen, etc.] with a metal, metal salt, or organometallic compound represented by the general formula M2 (8) to obtain a compound represented by the general formula (9): [wherein the symbols have the same meanings as defined above]. When V is a -W-R5 group, hydrolysis is further conducted. Thus, a compound of the general formula (10) is obtained.