499783-32-3

Basic information

• Product Name: Carbamic acid, [(1S)-2-hydroxy-3-[(4-methylphenyl)thio]-3-nitro-1-phenylpropyl]-, 1,1-dimethylethyl ester
• CAS NO: 499783-32-3
• Molecular Formula: C21H26N2O5S
• Molecular Weight: 418.514
• Mol File: 499783-32-3.mol

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [(1S)-2-hydroxy-3-[(4-methylphenyl)thio]-3-nitro-1-phenylpropyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(1S)-2-hydroxy-3-[(4-methylphenyl)thio]-3-nitro-1-phenylpropyl]-, 1,1-dimethylethyl ester(499783-32-3)
• EPA Substance Registry System: Carbamic acid, [(1S)-2-hydroxy-3-[(4-methylphenyl)thio]-3-nitro-1-phenylpropyl]-, 1,1-dimethylethyl ester(499783-32-3)

Safety Data

• Hazardous Substances Data: 499783-32-3(Hazardous Substances Data)

Upstream product

• 143978-88-5 N-tert-butoxycarbonyl-L-phenylglycine methyl ester 
• 150640-22-5 <(4-methylphenyl)thio>nitromethane 
• 163061-19-6 (2S)-2-tert-butoxycarbonylamino-2-phenylacetaldehyde 

Relevant articles and documents

Stereoselective synthesis of anti-β-amino-α-hydroxy acid derivatives using nucleophilic epoxidation of 1-arylthio-1-nitroalkenes

Reaction of lithium t-butylperoxide with 1-arylthio-1-nitroalkenes 5, prepared by condensation of (4-tolylthio)nitromethane with N-(Boc)-protected α-amino aldehydes, leads to the formation of oxazolidinones rather than the expected oxitranes. Initially, a mixture of cis 8 and trans 9 diastereoisomers is formed, but upon exposure to silica gel complete conversion to the cis-diastereoisomers 8 takes place.