499794-27-3Relevant academic research and scientific papers
A novel one-pot cycloisomerization-Wittig sequence with yne-allyl alcohols
Kressierer, Christoph J.,Müller, Thomas J. J.
, p. 655 - 658 (2004)
Alkyne allyl alcohols 1 are cycloisomerized under Pd catalysis to give γ,δ-enals 2 in moderate to good yields. These mild reaction conditions are fully compatible with a subsequent Wittig olefination. Thus, the cycloisomerization-Wittig olefination sequen
The first one-pot Alder-ene-reductive amination sequence
Kressierer, Christoph J.,Müller, Thomas J. J.
, p. 2155 - 2158 (2004)
Alkyne allyl alcohols 1 are cycloisomerized under Pd catalysis to give (4-alkylidene tetrahydrofuran-3-yl) acetaldehydes 2 in good yields. These mild reaction conditions are fully compatible with a subsequent reductive amination with secondary amines and formic acid. Thus, the cycloisomerization-reductive amination sequence of yne allyl alcohols 1 and secondary amines 3 furnishes β-amino ethyl alkylidene tetrahydrofurans 4 in moderate to good yields in a one-pot fashion.
Novel enantioselective sequentially rhodium(I)/BINAPcatalyzed cycloisomerization-hydrogenation-isomerizationacetalization (CIHIA)
Koerber, Nadine,Rominger, Frank,Mueller, Thomas J. J.
supporting information; experimental part, p. 2921 - 2935 (2010/08/04)
Linear, easily accessible alkyl and (hetero)aryl-substituted alkynyl allyl alcohols are readily and enantioselectively transformed into 2,7dioxabicyclo[3.2.1]octanes by a sequential rhodiumcatalyzed process. Based on the initial cycloisomerization, the in
A novel one-pot iridium-catalyzed alder-ene-murahashi sequence
Kummeter, Manuela,Ruff, Christian M.,Müller, Thomas J. J.
, p. 717 - 720 (2007/12/29)
Yne allyl alcohols could be transformed under very mild conditions by a novel iridium-catalyzed one-pot cycloisomerization-Murahashi sequence in 43-77% yield. Georg Thieme Verlag Stuttgart.
