500-08-3 Usage
Uses
Used in Pharmaceutical Industry:
Forminitrazole is used as a precursor in the synthesis of pharmaceuticals for its ability to contribute to the development of nitric oxide donating drugs. These drugs are crucial in treating various medical conditions due to the beneficial effects of nitric oxide in the body.
Used in Chemical Industry:
In the chemical industry, Forminitrazole is utilized in the formation of metal complexes for biological studies. Its reactivity and stability make it an ideal candidate for creating complexes that can be used in research to understand biological processes and develop new applications in life sciences.
Overall, Forminitrazole's applications span across different sectors, highlighting its importance in both pharmaceutical development and chemical research, underpinning its multifaceted utility in science and medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 500-08-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,0 and 0 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 500-08:
(5*5)+(4*0)+(3*0)+(2*0)+(1*8)=33
33 % 10 = 3
So 500-08-3 is a valid CAS Registry Number.
InChI:InChI=1/C4H3N3O3S/c8-2-6-4-5-1-3(11-4)7(9)10/h1-2H,(H,5,6,8)
500-08-3Relevant academic research and scientific papers
A fluorous and click approach for screening potential PET probes: Evaluation of potential hypoxia biomarkers
Bejot, Romain,Carroll, Laurence,Bhakoo, Kishore,Declerck, Jér?me,Gouverneur, Veronique
supporting information; experimental part, p. 324 - 329 (2012/03/10)
Radiopharmaceuticals for nuclear imaging are essentially targeting molecules, labeled with short-lived radionuclides (e.g., F-18 for PET). A significant drawback of radiopharmaceuticals development is the difficulty to access radiolabeled molecule libraries for initial in vitro evaluation, as radiolabeling has to be optimized for each individual molecule. The present paper discloses a method for preparing libraries of 18F-labeled radiopharmaceuticals using both the fluorous-based 18F-radiochemistry and the Huisgen 1,3-dipolar (click) conjugation reaction. As a proof of concept, this approach allowed us to obtain a series of readily accessible 18F-radiolabeled nitroaromatic molecules, for exploring their structure-activity relationship and further in vitro evaluation of their hypoxic selectivity.
