500004-93-3Relevant academic research and scientific papers
Synthesis of a novel tricyclic 4-quinolone. Incorporation of a spiro-cyclopropyl group at N1 by bridging to C2
Schroeder,Kiely
, p. 1769 - 1772 (1988)
An important pharmacophore in many quinolone antiinfectives is the N1 cyclopropane. By incorporating the cyclopropane into a N1 to C2 bridge, the first quinolone substrate incorporating a spiro fused cyclopropane, 8,9,10-trifluoro-2,3,4,6-tetrahydro-6-oxo
