500136-15-2 Usage
General Description
1,3-Pyrrolidinedicarboxylic acid, 5-thioxo-, dimethyl ester (9CI) is a chemical compound with the molecular formula C9H13NO4S. It is also known as baclofen and is commonly used as a muscle relaxant and antispasmodic medication. It works by inhibiting the transmission of impulses in the nervous system, specifically in the spinal cord. Baclofen is often prescribed to treat muscle symptoms caused by multiple sclerosis, spinal cord injuries, or other neurological disorders. It is available in both oral and injectable forms and is typically used in combination with physical therapy and other treatments. Baclofen may cause side effects such as drowsiness, dizziness, and weakness, and it should be used with caution in individuals with a history of seizures or kidney disease.
Check Digit Verification of cas no
The CAS Registry Mumber 500136-15-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,0,1,3 and 6 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 500136-15:
(8*5)+(7*0)+(6*0)+(5*1)+(4*3)+(3*6)+(2*1)+(1*5)=82
82 % 10 = 2
So 500136-15-2 is a valid CAS Registry Number.
500136-15-2Relevant academic research and scientific papers
Stanetty, Peter,Turner, Martin,Mihovilovic, Marko D.
, p. 367 - 375 (2005)
A route to methyl pyrrolo[2,3-d][1,2,3]thiadiazole-6-carboxylates as potential plant activators and inducers of systemic acquired resistance (SAR) is reported. A synthetic strategy based on cyclization of the thiadiazole ring system utilizing thionyl chloride via the Hurd-Mori protocol as key step was developed. Success of the ring closure reaction turned out to be highly dependent on the nature of the N-protecting group of the pyrrolidine precursor. While electron donors such as alkyl gave only poor conversion to the required 1,2,3-thiadiazoles, an electron withdrawing substituent such as methyl carbamate gave superior yields.