500533-15-3

Upstream product

• 251908-60-8 (2''S,4R,6R)-6-(2''-Benzyloxy-4''-pentenyl)-4-(methoxycarbonylmethyl)-2,2-dimethyl-1,3-dioxane 

Downstream Products

• 500533-20-0 tert-Butyl-{2-[(4S,6S)-6-((4R,6R)-6-{(4R,6S)-6-[(4R,6R)-6-(2,2-diphenyl-vinyl)-2,2-dimethyl-[1,3]dioxan-4-ylmethyl]-2,2-dimethyl-[1,3]dioxan-4-ylmethyl}-2,2-dimethyl-[1,3]dioxan-4-ylmethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-ethoxy}-dimethyl-silane 
• 500533-18-6 [(4R,6R)-6-((2S,4S,6S,8R)-2,8-Bis-benzyloxy-9-{(4R,6S)-6-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-4,6-dihydroxy-nonyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-acetic acid methyl ester 

Relevant academic research and scientific papers

Asymmetric synthesis of the polyol portion of the polyene macrolide antibiotic RK-397

A highly convergent and asymmetric synthesis of a fully functionalized polyol portion of the new polyene macrolide antibiotic RK-397 has been achieved taking advantage of a novel polyol synthesis.