500588-56-7

Upstream product

• 209985-44-4 2-[(α-isopropylthio)-N-(benzyloxycarbonyl)glycinyl]amino-4'-fluorobenzophenone 
• 3800-06-4 2-amino-4'-fluorobenzophenone 
• 124676-19-3 2-(benzotriazol-1-yl)-N-(benzyloxycarbonyl)glycine 

Downstream Products

• 1300086-96-7 phenylmethyl [6-(4-fluorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]carbamate 
• 1300089-68-2 C₂₃H₂₀FN₅O₂ 
• 1300089-35-3 phenylmethyl [5-(4-fluorophenyl)-2-thioxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]carbamate 

Relevant academic research and scientific papers

Condensed Azepine Derivatives As Bromodomain Inhibitors

Benzodiazepine compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and their use in therapy.

CONDENSED AZEPINE DERIVATIVES AS BROMODOMAIN INHIBITORS

Benzodiazepine compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and their use in therapy.

CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS

Disclosed are compounds which inhibit beta -amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits beta -amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.