500699-20-7Relevant articles and documents
A Highly Photostable Near-Infrared Labeling Agent Based on a Phospha-rhodamine for Long-Term and Deep Imaging
Grzybowski, Marek,Taki, Masayasu,Senda, Kieko,Sato, Yoshikatsu,Ariyoshi, Tetsuro,Okada, Yasushi,Kawakami, Ryosuke,Imamura, Takeshi,Yamaguchi, Shigehiro
, p. 10137 - 10141 (2018)
Various fluorescence microscopy techniques require bright NIR-emitting fluorophores with high chemical and photostability. Now, the significant performance improvement of phosphorus-substituted rhodamine dyes (PORs) upon substitution at the 9-position with a 2,6-dimethoxyphenyl group is reported. The thus obtained dye PREX 710 was used to stain mitochondria in living cells, which allowed long-term and three-color imaging in the vis-NIR range. Moreover, the high fluorescence longevity of PREX 710 allows tracking a dye-labeled biomolecule by single-molecule microscopy under physiological conditions. Deep imaging of blood vessels in mice brain has also been achieved using the bright NIR-emitting PREX 710-dextran conjugate.
SILICON-CONTAINING HETEROCYCLIC COMPOUND, AND QUENCHER
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, (2019/08/22)
Quenchers of the related art do not have a quenching ability high enough to sufficiently inhibit the emission of fluorescence from fluorescence compounds. Therefore, the present invention aims to provide a quencher which can sufficiently quench the fluore
Spirolactonized Si-rhodamine: A novel NIR fluorophore utilized as a platform to construct Si-rhodamine-based probes
Wang, Ting,Zhao, Qing-Jie,Hu, Hong-Gang,Yu, Shi-Chong,Liu, Xiang,Liu, Li,Wu, Qiu-Ye
supporting information; experimental part, p. 8781 - 8783 (2012/10/18)
Spirolactonized Si-rhodamine was prepared as a platform to construct Si-rhodamine-based probes by following the design strategy widely used in rhodamine systems. Among them, the reaction-based probe SiR-Hg was operated for NIR sensing and bioimaging of Hg