500760-53-2Relevant academic research and scientific papers
Elimination of a hydroxyl group in FTY720 dramatically improves the phosphorylation rate
Jary, Eve,Bee, Thomas,Walker, Scott R.,Chung, Sung-Kee,Seo, Kyung-Chang,Morris, Jonathan C.,Don, Anthony S.
, p. 685 - 692 (2010)
The new immunosuppressant FTY720 (fingolimod), an analog of the endogenous lipid sphingosine, induces transient lymphopenia through the sequestration of lymphocytes in secondary lymphoid organs. Phosphorylation of FTY720 by sphingosine kinase 2 (SphK2) yi
