500775-96-2Relevant academic research and scientific papers
Efficient solid phase synthesis of cleavable oligodeoxynucleotides based on a novel strategy for the synthesis of 5′-S-(4,4′-dimethoxytrityl)- 2′-deoxy-5′-thionucleoside phosphoramidites
Jahn-Hofmann, Kerstin,Engels, Joachim W.
, p. 2812 - 2828 (2007/10/03)
The incorporation of a specific cleavage site into an oligodeoxynucleotide can be achieved by utilizing the four 5′-S-(4,4′-dimethoxytrityl)- 2′-deoxy-5′-thionucleoside 3′-(2-cyanoethyl diisopropylphosphoramidites) 5 and 15a-c (Fig.1). Based on the silver
A new concept for DNA-arrays
Jahn-Hofmann, Kerstin,Holzhey, Nancy,Ellinger, Thomas,Engels, Joachim W.
, p. 1479 - 1482 (2007/10/03)
We will insert a cleavage site in an oligodeoxynucleotide, which can be used for a selective and quantitative cleavage. For that reason we synthesized the four 5′-S-(4,4′-dimethoxytrityl)-mercapto-2′ -deoxynucleotide-3′-O-(2-cyanoethoxydiisopropylamino)-p
