500903-64-0

Basic information

• Product Name: Carbamic acid, [5-(chlorocarbonyl)-1-methyl-1H-pyrrol-3-yl]-, 1,1-dimethylethyl ester
• CAS NO: 500903-64-0
• Molecular Formula: C11H15ClN2O3
• Molecular Weight: 258.705
• Mol File: 500903-64-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [5-(chlorocarbonyl)-1-methyl-1H-pyrrol-3-yl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [5-(chlorocarbonyl)-1-methyl-1H-pyrrol-3-yl]-, 1,1-dimethylethyl ester(500903-64-0)
• EPA Substance Registry System: Carbamic acid, [5-(chlorocarbonyl)-1-methyl-1H-pyrrol-3-yl]-, 1,1-dimethylethyl ester(500903-64-0)

Safety Data

• Hazardous Substances Data: 500903-64-0(Hazardous Substances Data)

Upstream product

• 26189-59-3 1-chloro-1-(dimethylamino)-2-methyl-1-propene 
• 77716-11-1 4-[(tert-butoxycarbonyl)amino]-1-methyl-1H-pyrrole-2-carboxylic acid 

Downstream Products

• 500903-66-2 (1-Methyl-5-methylcarbamoyl-1H-pyrrol-3-yl)-carbamic acid tert-butyl ester 
• 126092-96-4 methyl 4-<<(tert-butyloxy)carbonyl>amino>-1-methyl-pyrrole-2-carboxylate 

Relevant articles and documents

Fully Automated Synthesis of DNA-Binding Py-Im Polyamides Using a Triphosgene Coupling Strategy

The fully automated solid-phase synthetic strategy of hairpin pyrrole-imidazole polyamides is described. A key advance is the development of methodology for the application of triphosgene as a coupling agent in the automated synthesis of hairpin polyamides without racemization. This automated methodology is compatible with all the typical building blocks, enabling the facile synthesis of polyamide libraries in good yield (9-15%) and crude purity. (Chemical Equation Presented).

Aromatic and heteroaromatic acid halides for synthesizing polyamides

The present invention is directed to protected amino acid halide monomers and oligomers, and to their use in the efficient sythesis of polyamides. The present invention is further directed to the use of α-haloenamine reagents, which may optionally be immobilized, for the preparation of the amino acid halides.