501121-14-8

Basic information

• Product Name: Methanone, [5-(4-chlorophenyl)-2-oxazolyl]phenyl-
• CAS NO: 501121-14-8
• Molecular Formula: C16H10ClNO2
• Molecular Weight: 283.714
• Mol File: 501121-14-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Methanone, [5-(4-chlorophenyl)-2-oxazolyl]phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, [5-(4-chlorophenyl)-2-oxazolyl]phenyl-(501121-14-8)
• EPA Substance Registry System: Methanone, [5-(4-chlorophenyl)-2-oxazolyl]phenyl-(501121-14-8)

Safety Data

• Hazardous Substances Data: 501121-14-8(Hazardous Substances Data)

Upstream product

• 455-32-3 benzoyl fluoride 
• 1008-94-2 5-(4-chloro-phenyl)-oxazole 
• 104-88-1 4-chlorobenzaldehyde 
• 611-73-4 Benzoylformic acid 

Relevant articles and documents

Catalytic C?H/C?F Coupling of Azoles and Acyl Fluorides

A method for the palladium/copper-catalyzed direct acylation of azoles with acyl fluorides is described. This study reports the first examples of acyl fluorides being used as acylation reagents in transition-metal-catalyzed aromatic C?H bond functionalization reactions. Depending on the reaction temperature, decarbonylative coupling may also occur. Mechanistic studies suggest that the cleavage of the aromatic C?H bond, promoted by a copper-phosphine species, is not the rate-limiting step of this acylation.