501416-20-2

Upstream product

• 29782-85-2 rac-(trans)-2,2-dimethyl-3a,6a-dihydro-4H-cyclopenta[d][1,3]dioxol-4-ol 
• 501415-58-3 (-)-carbonic acid (1R,4R,5R)-4,5-isopropylidenedioxycyclopent-2-enyl ester methyl ester 
• 90870-33-0 N-(2-nitrobenzenesulfonyl)-N-(but-3-enyl)amine 
• 216015-22-4 (3aS,4R,6aR)-2,2-dimethyl-2H,3aH,4H,6aH-cyclopenta[d][1,3]-dioxol-4-ol 
• 301805-12-9 (-)-N-(but-3-enyl)-N-((1R,4R,5S)-4,5-isopropylidenedioxycyclopent-2-enyl)-2-nitrobenzenesulfonamide 

Downstream Products

• 501415-80-1 acetic acid (1S,2R,5R)-2-acetoxy-5-[allyl-(2-nitrobenzenesulfonyl)amino]cyclopent-3-enyl ester 
• 501415-85-6 (1S,2R)-2-(tert-butyl-dimethylsilanyloxy)-1-[(R)-1-(2-nitrobenzenesulfonyl)-1,2,5,6-tetrahydropyridin-2-yl]but-3-en-1-ol 
• 501415-83-4 (+)-acetic acid (1S,2R)-2-acetoxy-{[(R)-1-(2-nitrobenzenesulfonyl)-1,2,5,6-tetrahydropyridin-2-yl]methyl}allyl ester 
• 501415-84-5 (1S,2R)-1-[(R)-1-(2-nitrobenzenesulfonyl)-1,2,5,6-tetrahydropyridin-2-yl]but-3-ene-1,2-diol 
• 501416-17-7 p-toluenesulfonic acid (2R,3S)-2,3-bis-(tert-butyl-dimethylsilanyloxy)-3-[(R)-1-(2-nitrobenzenesulfonyl)-1,2,5,6-tetrahydropyridin-2-yl]-propyl ester 
• 301805-19-6 (3R,4S)-bis-(tert-butyl-dimethylsilanyloxy)-4-[(R)-1-(2-nitrobenzenesulfonyl)-1,2,5,6-tetrahydropyridin-2-yl]-butane-1,2-diol 
• 501416-16-6 (2R,3S)-2,3-bis-(tert-butyl-dimethylsilanyloxy)-3-[(R)-1-(2-nitrobenzenesulfonyl)-1,2,5,6-tetrahydropyridin-2-yl]-propan-1-ol 
• 301805-14-1 (+)-(R)-6-[(1S,2R)-1,2-bis-(tert-butyl-dimethylsilanyloxy)but-3-enyl]-1-(2-nitrobenzenesulfonyl)-1,2,3,6-tetrahydropyridine 
• 301805-13-0 (-)-N-(but-3-enyl)-N-{(1R,4R,5S)-4,5-bis-(tert-butyldimethylsilanyloxy)cyclopent-2-enyl}-2-nitrobenzenesulfonamide 

Relevant academic research and scientific papers

Asymmetric synthesis of indolizidine alkaloids by ring-closing-ring-opening metathesis

Asymmetric Pd(0) catalyzed allylic amination followed by a Ru catalyzed RCM-ROM sequence converted an easily accessible racemic cyclopentenol 2 to the functionalized tetrahydropyridine 9 which can be used for the asymmetrical synthesis of indolizidine 13.

Ruthenium catalyzed ring rearrangement: A rapid entry to substituted aza- and oxacycles

A ring-closing metathesis (RCM) and a ring-opening metathesis (ROM) are combined in a domino process giving access to a variety of aza- and oxacyles, equipped with highly functionalized side chains, starting from readily accessible cyclopentenyl or cycloh