501644-55-9

Upstream product

• 22577-14-6 2-(allyloxy)acetic acid 
• 56680-79-6 allyloxyacetyl chloride 
• 131744-19-9 (4S)-4-benzyl-1,3-oxazolidine-2-thione 

Downstream Products

• 866952-43-4 (2R,3R)-2-Allyloxy-1-((S)-4-benzyl-2-thioxo-oxazolidin-3-yl)-3-(tert-butyl-dimethyl-silanyloxy)-butan-1-one 
• 501644-58-2 (2R,3R)-2-Allyloxy-1-((S)-4-benzyl-2-thioxo-oxazolidin-3-yl)-3-hydroxy-butan-1-one 
• 501644-62-8 (2R,3R)-2-Allyloxy-1-((S)-4-benzyl-2-thioxo-oxazolidin-3-yl)-3-hydroxy-pent-4-en-1-one 
• 501644-61-7 (2R,3R)-2-Allyloxy-1-((S)-4-benzyl-2-thioxo-oxazolidin-3-yl)-3-hydroxy-4-methyl-pentan-1-one 
• 501644-60-6 (2R,3R)-2-Allyloxy-1-((S)-4-benzyl-2-thioxo-oxazolidin-3-yl)-3-hydroxy-octan-1-one 
• 501644-59-3 (2R,3R)-2-Allyloxy-1-((S)-4-benzyl-2-thioxo-oxazolidin-3-yl)-3-hydroxy-hexan-1-one 
• 501644-64-0 (2R,3R)-2-Allyloxy-1-((S)-4-benzyl-2-thioxo-oxazolidin-3-yl)-3-hydroxy-3-phenyl-propan-1-one 

Relevant academic research and scientific papers

Anti-selective aldol reactions with titanium enolates of N-glycolyloxazolidinethiones

(Matrix presented). A highly diastereoselective anti aldol addition utilizing a variety of N-glycolyloxazolidinethiones has been developed. Enolization of an N-glycolyloxazolidinethione with titanium (IV) chloride and (-)-sparteine followed by addition of an aldehyde activated with additional TiCl4 resulted in highly anti-selective aldol additions, typically with no observable syn isomers. Allyl-protected glycolates demonstrated the highest levels of selection and yields, although O-benzyl and O-methyl glycolyloxazolidinethiones also performed well.