501648-36-8Relevant academic research and scientific papers
Enantioselective Henry reaction catalyzed by C2-symmetric chiral diamine-copper(II) complex
Selvakumar, Sermadurai,Sivasankaran, Dhanasekaran,Singh, Vinod K.
supporting information; experimental part, p. 3156 - 3162 (2011/02/25)
A copper(II) complex of C2-symmetric diamine has been proved to be an efficient catalyst for the enantioselective Henry reaction between nitroalkanes and various aldehydes to provide β-hydroxy nitroalkanes in high yields (up to 97%), moderate diastereoselectivities (up to 71:29) and excellent enantiomeric excesses (up to 96%). The chiral nitroaldol adduct obtained has been further converted into chiral aziridine in few steps.
