124674-43-7Relevant academic research and scientific papers
Asymmetric synthesis of 3,4,6-trisubstituted 2,5-diketopiperazines by using dynamic kinetic resolution of α-bromo tertiary acetamides
Baek, Jinho,Kang, Seock Yong,Im, Chan,Park, Yong Sun
, p. 2780 - 2789 (2014/05/06)
A new and efficient method for the asymmetric synthesis of 3,4,6-trisubstituted 2,5-diketopiperazines has been developed. The dynamic kinetic resolution of L-amino-acid-derived α-bromo tertiary amides in the nucleophilic substitution reaction with p-anisi
Enantioselective Henry reaction catalyzed by C2-symmetric chiral diamine-copper(II) complex
Selvakumar, Sermadurai,Sivasankaran, Dhanasekaran,Singh, Vinod K.
supporting information; experimental part, p. 3156 - 3162 (2011/02/25)
A copper(II) complex of C2-symmetric diamine has been proved to be an efficient catalyst for the enantioselective Henry reaction between nitroalkanes and various aldehydes to provide β-hydroxy nitroalkanes in high yields (up to 97%), moderate diastereoselectivities (up to 71:29) and excellent enantiomeric excesses (up to 96%). The chiral nitroaldol adduct obtained has been further converted into chiral aziridine in few steps.
ELECTROREDUCTION D'UNE OXIME CHIRALE. OBTENTION D'UNE DICETOPIPERAZINE OPTIQUEMENT ACTIVE
Boulmedais, Ali,Jubault, Michel,Tallec, Andre
, p. 5497 - 5510 (2007/10/02)
Electrochemical reduction of methyl benzhydroxyiminoformyl (S)-prolinate leads to a mixture of the two epimers of pyrrolo 3-phenyl 1,4-diketopiperazine Separation and identification of the two isomers show that preferential formation of the SS epimer is always observed.The optical yield can reach 34percent.An explanation is proposed which takes in account influence of the electrolysis conditions (acidity of the medium, cathodic potential).
