501648-83-5

Upstream product

• 501648-78-8 ethyl (2R,3S)-5-benzyloxy-2,3-dihydroxypentanoate 
• 70542-83-5 ethyl (2E)-5-(benzyloxy)pent-2-enoate 
• 501648-79-9 ethyl (4R,5S)-5-(2-benzyloxyethyl)-2,2-dimethyl-1,3-dioxolane-4-carboxylate 
• 501648-81-3 ethyl (4R,5S)-5-(2-iodoethyl)-2,2-dimethyl-1,3-dioxolane-4-carboxylate 
• 501648-80-2 ethyl (4R,5S)-5-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolidine-4-carboxylate 
• 501648-82-4 ethyl (4R,5S)-2,2-dimethyl-5-[2-(4-nitrophenoxy)ethyl]-1,3-dioxolane-4-carboxylate 

Downstream Products

• 501648-84-6 ethyl (2R,3S)-3-hydroxy-5-(4-nitrophenoxy)-2-[(2-nitrophenylsulfonyl)oxy]pentanoate 

Relevant academic research and scientific papers

A selective HIV-protease assay based on a chromogenic amino acid

(2S,3S)-2-Amino-3-hydroxy-5-(4-nitrophenoxy)pentanoic acid (5) was prepared stereoselectively as the N-Fmoc, O-(tert-butyl)-protected derivative 5a in eleven steps from ethyl (E)-4-benzyloxypent-2-enoate (6). This protected amino acid was used for the sol