501680-65-5

Basic information

• Product Name: 2-p-tolylsulfanylquinoline
• Synonyms: 2-p-tolylsulfanylquinoline
• CAS NO: 501680-65-5
• Molecular Weight: 251.352
• Mol File: 501680-65-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-p-tolylsulfanylquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-p-tolylsulfanylquinoline(501680-65-5)
• EPA Substance Registry System: 2-p-tolylsulfanylquinoline(501680-65-5)

Safety Data

• Hazardous Substances Data: 501680-65-5(Hazardous Substances Data)

Upstream product

• 612-62-4 2-Chloroquinoline 
• 2005-43-8 2-bromoquinoline 
• 106-45-6 para-thiocresol 

Downstream Products

• 612-96-4 2-Phenylquinoline 

Relevant articles and documents

Nickel-Catalyzed Thiolation of Aryl Halides and Heteroaryl Halides through Electrochemistry

Transition-metal-catalyzed coupling reactions are useful tools for synthesizing aryl sulfur compounds. However, conventional transition-metal-catalyzed thiolation of aryl bromides and chlorides typically requires the use of strong base under elevated reaction temperature. Herein, we report the first examples of nickel-catalyzed electrochemical thiolation of aryl bromides and chlorides in the absence of an external base at room temperature using undivided electrochemical cells.

Catalyst-free and base-free water-promoted SNAr reaction of heteroaryl halides with thiols

A simple and efficient route for the synthesis of biaryl sulfides have been developed in aqueous medium under base- and catalyst-free conditions. A wide variety of heteroaryl halides and thiols underwent SNAr reaction to provide diaryl sulfides in good to excellent yields. The remarkable key features of the reaction include the use of water as an inexpensive and environmentally benign reaction medium, absence of any additional reagent or catalyst, and easy isolation of the products. Georg Thieme Verlag Stuttgart.