501691-18-5Relevant academic research and scientific papers
RENIN INHIBITORS
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Page/Page column 200; 205, (2008/12/07)
Compounds, pharmaceutical compositions, kits, article of manufacture, methods of using, and method of preparing of compounds having the formula of : wherein the variables are as defined herein.
N-H insertion reactions of primary ureas: The synthesis of highly substituted imidazolones and imidazoles from diazocarbonyls
Lee, Sang-Hyeup,Yoshida, Kazuhiro,Matsushita, Hana,Clapham, Bruce,Koch, Guido,Zimmermann, Juerg,Janda, Kim D.
, p. 8829 - 8835 (2007/10/03)
Primary ureas have been used as substrates in rhodium-catalyzed N-H insertion reactions with an array of diazocarbonyls. The insertion reaction is efficient and gives excellent selectivity and yields. The products from the insertion reaction with diazoket
Rhodium carbenoid N-H insertion reactions of primary ureas: solution and solid-phase synthesis of imidazolones.
Lee, Sang-Hyeup,Clapham, Bruce,Koch, Guido,Zimmermann, Juerg,Janda, Kim D
, p. 511 - 514 (2007/10/03)
[reaction: see text] The solution and solid-phase synthesis of imidazolones is reported. The key step for the preparation of these compounds is the N-H insertion reaction of primary ureas into highly reactive rhodium carbenoid intermediates. Typically, a
