501698-03-9

Usage

Uses

Used in Oncology:
Urea, N-[4-(4-aminothieno[2,3-d]pyrimidin-5-yl)phenyl]-N'-(3-methylphenyl)-, is used as an antineoplastic agent for the treatment of various types of cancers. Its application is particularly relevant in cases where there is an overexpression of certain molecular targets, as it can effectively target and inhibit these pathways, leading to a reduction in cancer cell proliferation.
Used in Cancer Research:
This urea derivative is also used in cancer research to explore its potential as a therapeutic agent. Researchers are investigating its mechanism of action, specificity, and efficacy in targeting cancer cells, as well as its potential synergistic effects when combined with other treatments.
Used in Drug Development:
Urea, N-[4-(4-aminothieno[2,3-d]pyrimidin-5-yl)phenyl]-N'-(3-methylphenyl)-, is a promising candidate for drug development due to its potential antineoplastic activity. Pharmaceutical companies and research institutions are actively studying its properties and exploring ways to optimize its therapeutic potential, with the aim of developing novel cancer treatments.
Used in Targeted Therapies:
In the field of targeted therapies, Urea, N-[4-(4-aminothieno[2,3-d]pyrimidin-5-yl)phenyl]-N'-(3-methylphenyl)-, is used to develop drugs that specifically target molecular pathways involved in cancer cell growth and proliferation. This approach can potentially lead to more effective treatments with fewer side effects compared to traditional chemotherapy.

Upstream product

• 86604-41-3 2-amino-4-(4-nitrophenyl)thiophene-3-carbonitrile 
• 501696-27-1 5-(4-nitrophenyl)thieno[2,3-d]pyrimidin-4-amine 
• 621-29-4 3-tolyl isocyanate 
• 100-19-6 (4-nitrophenyl)ethanone 
• 26088-96-0 2-[1-(4-nitrophenyl)ethylidene]malononitrile 
• 501696-28-2 5-(4-aminophenyl)thieno[2,3-d]pyrimidin-4-amine 

Relevant academic research and scientific papers

A One-Step, Atom Economical Synthesis of Thieno[2,3-d]pyrimidin-4-amine Derivatives by a Four-Component Reaction

A Na2HPO4-catalyzed four-component reaction between a ketone, malononitrile, S8 and formamide has been realized for the first time. This reaction provides a concise approach to thieno[2,3-d]pyrimidin-4-amines, previously r

New conditions for the synthesis of thiophenes via the Knoevenagel/Gewald reaction sequence. Application to the synthesis of a multitargeted kinase inhibitor

Novel conditions have been developed for the preparation of substituted 2-aminothiophenes employing the Knoevenagel condensation followed by the Gewald reaction. The benefits of these conditions are their mildness, and the ease of product isolation. Thus,

Thienopyrimidine ureas as novel and potent multitargeted receptor tyrosine kinase inhibitors

A series of novel thienopyrimidine-based receptor tyrosine kinase inhibitors has been discovered. Investigation of structure-activity relationships at the 5- and 6-positions of the thienopyrimidine nucleus led to a series of N,N′-diaryl ureas that potentl

Thiopyrimidine and isothiazolopyrimidine kinase inhibitors

Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.

Thiopyrimidine and isothiazolopyrimidine kinase inhibitors

Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.

Thiopyrimidine and isothiazolopyrimidine kinase inhibitors

Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compound, compositions containing the compounds, and methods of treatment using the compounds.