5018-45-1 Usage
Uses
Used in Pharmaceutical Industry:
5,6-Dimethoxypyrimidin-4-ylamine is used as an impurity in the synthesis of Sulfadoxine (S699070), an antibacterial agent. Sulfadoxine is a sulfonamide antibiotic that is commonly used in combination with other drugs, such as pyrimethamine, to treat various bacterial infections, including urinary tract infections, bronchitis, and traveler's diarrhea.
As an intermediate in the synthesis of other pharmaceutical compounds, 5,6-Dimethoxypyrimidin-4-ylamine can be further modified or reacted with other molecules to produce a variety of therapeutic agents with different applications in the medical field. Its unique chemical structure allows for potential use in the development of new drugs targeting various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 5018-45-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,0,1 and 8 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 5018-45:
(6*5)+(5*0)+(4*1)+(3*8)+(2*4)+(1*5)=71
71 % 10 = 1
So 5018-45-1 is a valid CAS Registry Number.
InChI:InChI=1/C6H9N3O2/c1-10-4-5(7)8-3-9-6(4)11-2/h3H,1-2H3,(H2,7,8,9)
5018-45-1Relevant academic research and scientific papers
METHOD FOR PRODUCING HIGHLY PURE CRYSTALLINE 4-AMINO-5,6-DIMETHOXYPYRIMIDINE
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Page/Page column 7-8, (2008/06/13)
The invention relates to a method for producing highly pure crystalline 4-amino-5,6-dimethoxypyrimidine by: a) reacting 4-amino-6-chloro-5-methoxypyrimidine with methanol and with a base at a temperature ranging from 20 to 100 °C, whereby: b) the methanolic solvent is entirely or partially replaced by water; c) the aqueous or aqueous/methanolic solution is extracted using t-butyl methyl ether, and; d) the extracted product is crystallized out of the t-butyl methyl ether. It has been surprisingly shown that an extremely pure and crystalline 4-amino-5,6-dimethoxypyrimidine can be produced with a high yield by using t-butyl methyl ether as an extracting agent. In addition, the method can be carried out in a comparatively technically simple manner.
