501923-65-5Relevant academic research and scientific papers
Synthesis of a simplified bryostatin C-ring analogue that binds to the CRD2 of human PKC-α and construction of a novel BC-analogue by an unusual julia olefination process
Hale, Karl J.,Frigerio, Mark,Manaviazar, Soraya,Hummersone, Marc G.,Fillingham, Ian J.,Barsukov, Igor G.,Damblon, Christian F.,Gescher, Andreas,Roberts, Gordon C. K.
, p. 499 - 502 (2003)
(Matrix presented) The synthesis of two truncated bryostatin analogues 2 and 3 is described. High-field NMR measurements on the C-ring analogue 3 in C2H3CN containing 25% 2H2O have shown that it binds to the CRD
