502-95-4Relevant articles and documents
Synthesis of fluorous tags for incorporation of reducing sugars into a quantitative microarray platform
Chen, Guo-Song,Pohl, Nicola L.
, p. 785 - 788 (2008)
Carbohydrate microarrays can map out key interactions of carbohydrates and proteins in a high-throughput manner, but require the inclusion of a range of sugars for their optimal use. Here we present the synthesis and use of a new hydroxylamine-modified fluorous tag that allows the facile incorporation of reducing sugars into a noncovalent fluorous-based microarray after simple purification by fluorous solid-phase extraction (FSPE). The microarray supports quantitative screening against carbohydrate-binding proteins.
The normal coordinate analysis of cyclic succinhydrazide (tetrahydro-3,6-pyridazinedione)
Asai, Masatomo,Noda, Kunio,Sado, Akira
, p. 703 - 712 (1985)
The i.r. spectra of cyclic succinhydrazide and cyclic succinhydrazide-d2 in the solid state have been measured in the region between 4000 and 250 cm-1.The normal coordinate analysis has been performed as a 14-body problem with C2 molecular symmetry.A simple Urey-Bradley force field has been used and the force constants have been refined by the least squares method.The vibrational assignments have been made on the basis of the calculated frequencies and the potential energy distributions.The calculated frequencies in both isotopic species were in good agreement with the observed frequencies.The skeletal streching force constants have been compared with those of glycine anhydride.Consequently, it has been found that in the cyclic succinhydrazide molecule the double bond is delocalized throughout the bonds O=C-N-N-C=O.
One-pot, four-component synthesis of new 3,4,7,8-tetrahydro-3,3-dimethyl-11-aryl-2H-pyridazino[1,2-a]indazole-1,6,9(11H)-triones and 2H-indazolo[2,1-b]phthalazine-1,6,11(13H)-triones using an acidic ionic liquid N,N-diethyl-N-sulfoethanammonium chloride ([Et3N-SO3H]Cl) as a highly efficient and recyclable catalyst
Pouramiri, Behjat,Tavakolinejad Kermani, Esmat
supporting information, p. 1006 - 1010 (2016/02/16)
A rapid and efficient one-pot, four-component protocol for the synthesis of novel 2H-pyridazino[1,2-a]indazole-1,6,9(11H)-triones (6) and 2H-indazolo[2,1-b]phthalazine-1,6,11-triones (7) has been developed using a stable and reusable Br?nsted acidic ionic liquid N,N-diethyl-N-sulfoethanammonium chloride ([Et3N-SO3H]Cl). A range of diverse aldehydes were successfully applied and the corresponding products obtained in good to excellent yields without any by-products.
Effect of remote trigonal carbons on the kinetics of Bergman cyclization: Synthesis and chemical reactivity of pyridazinedione-based enediynes
Basak, Amit,Bag, Subhendu Sekhar,Majumder, Pooja Anjali,Das, Amit Kumar,Bertolasi, Valerio
, p. 6927 - 6930 (2007/10/03)
The synthesis and chemical reactivity of pyridazinedione-based enediynes (1, 2) are described. Both of these enediynes, namely the dihydro compound 1 and its corresponding tetrahydro analogue 2, were prepared by double N,O-alkylation of the corresponding