502185-64-0

Upstream product

• 100-39-0 benzyl bromide 
• 791837-61-1 4-O-(2-acetamido-6-O-benzyl-2-deoxy-3,4-O-isopropylidene-β-D-talopyranosyl)-2,3:5,6-di-O-isopropylidene-aldehydo-D-glucose dimethyl acetal 
• 791837-62-2 4-O-(2-acetamido-6-O-benzyl-2-deoxy-β-D-talopyranosyl)-2,3-O-isopropylidene-aldehydo-D-glucose dimethyl acetal 
• 791837-63-3 4-O-(2-acetamido-6-O-benzyl-2-deoxy-β-D-talopyranosyl)-2,3:5,6-di-O-isopropylidene-aldehydo-D-glucose dimethyl acetal 
• 791837-64-4 4-O-(2-acetamido-3,6-di-O-benzyl-2-deoxy-β-D-talopyranosyl)-2,3:5,6-di-O-isopropylidene-aldehydo-D-glucose dimethyl acetal 
• 263845-21-2 4-O-(2-acetamido-2-deoxy-3,4-O-isopropylidene-6-O-trityl-β-D-talopyranosyl)-2,3:5,6-di-O-isopropylidene-aldehydo-D-glucose dimethyl acetal 
• 263845-22-3 4-O-[2-acetamido-2-deoxy-3,4-O-isopropylidene-β-D-talopyranosyl]-2,3:5,6-di-O-isopropylidene-aldehydo-D-glucose dimethyl acetal 
• 432038-81-8 4-O-(2-acetamido-3,6-di-O-benzyl-2,4-dideoxy-β-D-threo-hex-3-enopyranosyl)-2,3:5,6-di-O-isopropylidene-aldehydo-D-glucose dimethyl acetal 

Downstream Products

• 1245785-38-9 4-O-(2-acetamido-3,6-di-O-benzyl-2-deoxy-β-D-mannopyranosyl)-2,3-O-isopropylidene-D-xylo-hexos-5-ulose dimethyl acetal 
• 1245785-40-3 4-O-(2-acetamido-4-O-acetyl-3,6-di-O-benzyl-2-deoxy-β-D-mannopyranosyl)-N-benzyl-2,3,6-tri-O-acetyl-1,5-di-deoxy-1,5-imino-D-glucitol 
• 1245785-36-7 4-O-(2-acetamido-3,6-di-O-benzyl-2-deoxy-β-D-mannopyranosyl)-2,3-O-isopropylidene-aldehydo-D-glucose dimethyl acetal 

Relevant academic research and scientific papers

A new preparation of the disaccharide β-D-ManNAcp-(1 → 4)-D-Glc from lactose through a highly stereoselective β-D-Galp to β-D-ManNAcp transformation

A new method for the construction of the β-D-ManNAcp-(1 → 4)-D-Glc framework from lactose avoiding the β-mannosaminylation step was developed starting from 4-O-(2-acetamido-2-deoxy-3,4-O-isopropylidene-6-O- trityl-β-D-talopyranosyl)-2,3 : 5,6-di-O-isoprop

A new stereocontrolled access to β-D-mannopyranosides and 2-acetamido-2-deoxy-β-D-mannopyranosides starting from β-D-galactopyranosides

A new stereocontrolled synthesis of β-D-mannopyranosides was defined relying on a high yielding sequence based on the following three key steps: (a) a stereospecific inversion at C-2 of β-D-galactopyranosides by an oxidation-reduction procedure; (b) a regiocontrolled formation of 4-deoxy-β-D-threo-hex-3-enopyranosides; (c) a regio- and stereocontrolled hydroboration-oxidation of the above enol ethers. The flexibility of this new method was demonstrated by its extension to the synthesis of 2-acetamido-2-deoxy-β-D-mannopyranosides and of an orthogonally protected β-D-mannopyranoside scaffold and, finally, by the transformation of lactose into the two biologically relevant disaccharides with primary structure β-D-Manp-(1→4)-D-Glc and β-D-ManNAcp-(1→4)-D-Glc.