502618-02-2Relevant articles and documents
Novel synthesis of 2-naphthol Mannich bases and their NMR behaviour
Jha, Amitabh,Paul, Nawal K.,Trikha, Smriti,Cameron, T. Stanley
, p. 843 - 853 (2006)
A novel two-step procedure involving the formation of 1-arylidene-2- tetralones from 2-tetralone and subsequent Michael addition of a cyclic secondary amine on the alkenone followed by in situ aerial oxidation was developed to produce 2-naphthol Mannich bases. A simple microwave-assisted one-pot synthesis of 2-naphthol Mannich bases was also carried out under solvent-free conditions from 2-naphthol and corresponding aldehydes and amines in the presence of p-toluenesulfonic acid. The compounds of this series displayed interesting NMR behaviour. Extensive variable-temperature NMR investigations, including HSQC experiments, are herein reported. NMR results on the conformation in solution phase were found to be consistent with the X-ray crystal structure in the solid state.
Tandem Rh-Catalyzed [4 + 2] Vinylic C-H O-Annulation of Exocyclic Enones with Alkynes and 1,5-H Shift
Zhao, Yinsong,Yu, Chuangui,Wang, Tianbao,She, Zhijie,Zheng, Xuesong,You, Jingsong,Gao, Ge
supporting information, p. 1074 - 1077 (2018/02/23)
Active pyrylium intermediates are in situ generated by a Rh-catalyzed vinylic C-H annulation reaction between exocyclic α,β-enones and alkynes, which undergo a base-promoted rearrangement via 1,5-H shift to form 1H-benzo[f]chromene derivatives.
