502622-83-5Relevant articles and documents
The TosMIC approach to 3-(oxazol-5-yl) indoles: Application to the synthesis of indole-based IMPDH inhibitors
Dhar,Shen, Zhongqi,Fleener, Catherine A.,Rouleau, Katherine A.,Barrish, Joel C.,Hollenbaugh, Diane L.,Iwanowicz, Edwin J.
, p. 3305 - 3308 (2002)
A modified approach to the synthesis of 3-(oxazolyl-5-yl) indoles is reported. This method was applied to the synthesis of series of novel indole based inhibitors of inosine monophosphate dehydrogenase (IMPDH). The synthesis and the structure-activity rel