Bioorganic and Medicinal Chemistry Letters p. 3305 - 3308 (2002)
Update date:2022-08-02
Topics:
Dhar
Shen, Zhongqi
Fleener, Catherine A.
Rouleau, Katherine A.
Barrish, Joel C.
Hollenbaugh, Diane L.
Iwanowicz, Edwin J.
A modified approach to the synthesis of 3-(oxazolyl-5-yl) indoles is reported. This method was applied to the synthesis of series of novel indole based inhibitors of inosine monophosphate dehydrogenase (IMPDH). The synthesis and the structure-activity rel
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