502689-87-4

Basic information

• Product Name: 4(1H)-Pyridinone, 2-methyl-5-(phenylmethoxy)-1-[2-(2-pyridinyl)ethyl]-
• CAS NO: 502689-87-4
• Molecular Formula: C20H20N2O2
• Molecular Weight: 320.391
• Mol File: 502689-87-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4(1H)-Pyridinone, 2-methyl-5-(phenylmethoxy)-1-[2-(2-pyridinyl)ethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 4(1H)-Pyridinone, 2-methyl-5-(phenylmethoxy)-1-[2-(2-pyridinyl)ethyl]-(502689-87-4)
• EPA Substance Registry System: 4(1H)-Pyridinone, 2-methyl-5-(phenylmethoxy)-1-[2-(2-pyridinyl)ethyl]-(502689-87-4)

Safety Data

• Hazardous Substances Data: 502689-87-4(Hazardous Substances Data)

Upstream product

• 644-46-2 allomaltol 
• 501-30-4 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 
• 7559-81-1 chlorokojic acid 
• 2706-56-1 2-(aminoethyl)pyridine 
• 100397-13-5 5-(benzyloxy)-2-methyl-4H-pyran-4-one 

Relevant articles and documents

New analgesic and antiinflammatory agents 4(1H)-pyridinone derivatives

A series of 1,2,5-trisubstituted 4(1H)-pyridinone derivatives (7-14) were synthesised by using 4-pyrone derivatives with primary amines in ethanol. The structures of the synthesised compounds were confirmed by analytical and spectral data (UV, IR and 1H-NMR and microanalysis). Analgesic and antiinflammatory activities of the synthesised compounds were investigated by acetic acid-induced writhing syndrome and carrageenan rat paw edema tests. All of the test compounds exhibited higher analgesic activities than acetyl salicylic acid and showed higher antiinflammatory activities than indomethacin. The antiinflammatory activity and gastric ulceration potential of the compounds were tested using indomethacin as reference drug.