502697-61-2 Usage
Uses
Used in Pharmaceutical Industry:
Carbamic acid, [(3S)-3-hydroxy-3-phenylpropyl]-, ethyl ester is used as a pharmaceutical intermediate for the synthesis of various drugs. Its unique structure allows it to be a versatile building block in the development of new pharmaceutical compounds.
Used in Organic Synthesis:
In the field of organic synthesis, Carbamic acid, [(3S)-3-hydroxy-3-phenylpropyl]-, ethyl ester serves as a key component in the synthesis of complex organic molecules. Its reactivity and functional groups make it a valuable precursor for the creation of a wide range of organic compounds.
Used in Medicinal Chemistry:
Due to its potential biological activity, Carbamic acid, [(3S)-3-hydroxy-3-phenylpropyl]-, ethyl ester is of interest in medicinal chemistry. It may be used as a starting point for the development of new drugs or as a tool to study biological processes and mechanisms. Further research and testing would be required to fully understand its potential in this field.
Check Digit Verification of cas no
The CAS Registry Mumber 502697-61-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,2,6,9 and 7 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 502697-61:
(8*5)+(7*0)+(6*2)+(5*6)+(4*9)+(3*7)+(2*6)+(1*1)=152
152 % 10 = 2
So 502697-61-2 is a valid CAS Registry Number.
502697-61-2Relevant academic research and scientific papers
Chemoenzymatic synthesis2 of both enantiomers of fluoxetine, tomoxetine and nisoxetine: Lipase-catalyzed resolution of 3-aryl-3-hydroxypropanenitriles
Kamal, Ahmed,Khanna,Ramu
, p. 2039 - 2051 (2007/10/03)
A facile preparation of (±)-3-hydroxy-3-phenylpropanenitrile has been carried out by ring-opening of styrene oxide with NaCN in aqueous ethanol. Subsequent kinetic resolution of this material via lipase-mediated transesterification gave the S-alcohol and R-acetate in excellent yields and high enantioselectivities, particularly with lipase PS-C 'Amano' II. The effect of solvents and immobilization of the lipase has also been investigated. It is interesting to note that the use of immobilized lipase for this transesterification process in hydrophobic solvents (diisopropyl ether, toluene and hexane) enhanced the reaction rate drastically and gave optimal yields with high enantioselectivity (>99%). Moreover, enantiopure 3-hydroxy-3-phenylpropanenitrile products have been converted via enantioconvergent routes into the (R)- and (S)-enantiomers of the important anti-depressants fluoxetine, tomoxetine, nisoxetine and norfluoxetine.
