5028-15-9

Basic information

• Product Name: 1-METHYL-4-(3-NITRO-2-PYRIDINYL)PIPERAZINE
• Synonyms: 1-METHYL-4-(3-NITRO-2-PYRIDINYL)PIPERAZINE;1-Methyl-4-(3-nitro-2-pyridinyl)piperazine ,97%;Piperazine,1-methyl-4-(3-nitro-2-pyridinyl)-;1-methyl-4-(3-nitropyridin-2-yl)piperazine
• CAS NO: 5028-15-9
• Molecular Formula: C10H14N4O2
• Molecular Weight: 222.24
• Mol File: 5028-15-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 130°C 1mm
• Flash Point: 171.1°C
• Appearance: /
• Density: 1.249g/cm³
• Vapor Pressure: 2.4E-05mmHg at 25°C
• Refractive Index: 1.582
• CAS DataBase Reference: 1-METHYL-4-(3-NITRO-2-PYRIDINYL)PIPERAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-METHYL-4-(3-NITRO-2-PYRIDINYL)PIPERAZINE(5028-15-9)
• EPA Substance Registry System: 1-METHYL-4-(3-NITRO-2-PYRIDINYL)PIPERAZINE(5028-15-9)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 5028-15-9(Hazardous Substances Data)

Usage

General Description

1-Methyl-4-(3-nitro-2-pyridinyl)piperazine is a chemical compound that belongs to the piperazine class of organic compounds. It is a derivative of piperazine with a nitro-substituted pyridine ring, and it is widely used in the pharmaceutical industry as a building block for the synthesis of various drugs. 1-METHYL-4-(3-NITRO-2-PYRIDINYL)PIPERAZINE has been researched for its potential therapeutic effects in the treatment of various conditions, including cancer and neurological disorders. Its structure and properties make it a versatile molecule with potential applications in drug discovery and development. However, it is important to note that this compound may pose hazards if not handled and used properly, and caution should be exercised when working with it in a laboratory or industrial setting.

InChI:InChI=1/C10H14N4O2/c1-12-5-7-13(8-6-12)10-9(14(15)16)3-2-4-11-10/h2-4H,5-8H2,1H3

Upstream product

• 109-01-3 1-methyl-piperazine 
• 5470-18-8 2-Chloro-3-nitropyridine 

Downstream Products

• 5028-17-1 2-(4-methylpiperazin-1-yl)pyridin-3-amine 

Relevant articles and documents

METHODS OF USING INDAZOLE-3-CARBOXAMIDES AND THEIR USE AS WNT/B-CATENIN SIGNALING PATHWAY INHIBITORS

This disclosure features the use of one or more indazole-3-carboxamide compounds or salts or analogs thereof, in the treatment of one or more diseases or conditions independently selected from the group consisting of a tendinopathy, dermatitis, psoriasis, morphea, ichthyosis, Raynaud's syndrome, and Darier's disease; and/or for promoting wound healing. The methods include administering to a subject (e.g., a subject in need thereof) a therapeutically effective amount of one or more indazole-3-carboxamide compounds or salts or analogs thereof as described anywhere herein.

PIPERAZINYLPHENALKYL LACTAM/AMINE LIGANDS FOR THE 5HT1B RECEPTOR

The present invention relates to novel derivatives, that are compounds of Formula (I), wherein R1, R2, R3, R14, X, Y, n and m are defined herein, their pharmaceutically acceptable salts, pharmaceutical compositions and methods using said compounds in treating or preventing depression, anxiety, obsessive compulsive disorder (OCD) and other disorders for which selective antagonists, inverse agonists and partial agonists of serotonin 1 (5-HT1) receptors, specifically, antagonists of 5-HT1B are useful.