5028-17-1

Usage

Uses

Used in Pharmaceutical Development:
2-(4-METHYLPIPERAZINO)-3-PYRIDINAMINE is utilized as a key component in the synthesis of pharmaceutical drugs due to its versatile chemical structure and pharmacological properties. It serves as a fundamental building block, contributing to the development of new medications with potential applications in various therapeutic areas.
Used in Antitumor Applications:
In the field of oncology, 2-(4-METHYLPIPERAZINO)-3-PYRIDINAMINE is employed as an antitumor agent. Its reported antitumor activities make it a valuable compound for the development of drugs aimed at treating cancer. 2-(4-METHYLPIPERAZINO)-3-PYRIDINAMINE's ability to target and inhibit the growth of tumor cells could lead to the creation of novel cancer therapies.
Used in Antifungal Applications:
2-(4-METHYLPIPERAZINO)-3-PYRIDINAMINE also finds use in antifungal applications. Its demonstrated antifungal properties suggest that it could be instrumental in developing new treatments for fungal infections, offering an alternative or adjunct to existing antifungal medications.
Used in Medicinal Chemistry Research:
In the realm of medicinal chemistry research, 2-(4-METHYLPIPERAZINO)-3-PYRIDINAMINE is used as a subject of study for understanding its structure-activity relationships and exploring its potential in the development of new drugs. Researchers leverage its chemical and biological characteristics to design and synthesize novel compounds with improved therapeutic profiles.

InChI:InChI=1/C10H16N4/c1-13-5-7-14(8-6-13)10-9(11)3-2-4-12-10/h2-4H,5-8,11H2,1H3

Upstream product

• 109-01-3 1-methyl-piperazine 
• 6298-19-7 2-chloro-3-aminopyridine 
• 220499-48-9 6-bromo-2-(4-methyl-piperazin-1-yl)-pyridin-3-ylamine 
• 5470-18-8 2-Chloro-3-nitropyridine 
• 5028-15-9 1-methyl-4-(3-nitro-pyridin-2-yl)-piperazine 
• 39856-57-0 2,6-dibromo-3-aminopyridine 

Relevant academic research and scientific papers

METHODS OF USING INDAZOLE-3-CARBOXAMIDES AND THEIR USE AS WNT/B-CATENIN SIGNALING PATHWAY INHIBITORS

This disclosure features the use of one or more indazole-3-carboxamide compounds or salts or analogs thereof, in the treatment of one or more diseases or conditions independently selected from the group consisting of a tendinopathy, dermatitis, psoriasis, morphea, ichthyosis, Raynaud's syndrome, and Darier's disease; and/or for promoting wound healing. The methods include administering to a subject (e.g., a subject in need thereof) a therapeutically effective amount of one or more indazole-3-carboxamide compounds or salts or analogs thereof as described anywhere herein.

INDAZOLE-3-CARBOXAMIDES AND THEIR USE AS WNT/B-CATENIN SIGNALING PATHWAY INHIBITORS

lndazole-3-carboxamide compounds for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of an indazole-3- carboxamide compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.

PIPERAZINYLPHENALKYL LACTAM/AMINE LIGANDS FOR THE 5HT1B RECEPTOR

The present invention relates to novel derivatives, that are compounds of Formula (I), wherein R1, R2, R3, R14, X, Y, n and m are defined herein, their pharmaceutically acceptable salts, pharmaceutical compositions and methods using said compounds in treating or preventing depression, anxiety, obsessive compulsive disorder (OCD) and other disorders for which selective antagonists, inverse agonists and partial agonists of serotonin 1 (5-HT1) receptors, specifically, antagonists of 5-HT1B are useful.