502925-47-5Relevant academic research and scientific papers
Metal-Free Aerobic Oxidative Selective C-C Bond Cleavage in Heteroaryl-Containing Primary and Secondary Alcohols
Xia, Anjie,Qi, Xueyu,Mao, Xin,Wu, Xiaoai,Yang, Xin,Zhang, Rong,Xiang, Zhiyu,Lian, Zhong,Chen, Yingchun,Yang, Shengyong
supporting information, (2019/05/07)
A transition-metal-free aerobic oxidative selective C-C bond-cleavage reaction in primary and secondary heteroaryl alcohols is reported. This reaction was highly efficient and tolerated various heteroaryl alcohols, generating a carboxylic acid derivative and a neutral heteroaromatic compound. Experimental studies combined with density functional theory calculations revealed the mechanism underlying the selective C-C bond cleavage. This strategy also provides an alternative simple approach to carboxylation reaction.
1-aryl-3-(6-arylpyridine-2-yl)-acrylketone, and preparation method and application thereof
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Paragraph 0031; 0033; 0038; 0047; 0048, (2019/11/12)
The invention relates to 1-aryl-3-(6-arylpyridine-2-yl)-acrylketone. The molecular structure of the compound is shown in the following general formula: in the general formula, R1 is hydrogen or methoxy, R2 is hydrogen or methoxy, R3 is hydrogen or methoxy
Convenient and rapid strategies towards 6-(hetero)aryl pyridylmethylamines: First catalytic issues
Requet, Alexandre,Yalgin, Hasret,Prim, Damien
supporting information, p. 1378 - 1382 (2015/03/04)
The convenient preparation of new pyridylmethylamines is described using a short two step sequence. The first step involved the straightforward microwave-assisted construction of 6-aryl and 6-heteroaryl pyridine scaffolds bearing carboxaldehyde and nitrile fragments. The pendant arm comprising a second nitrogen atom by mean of amine and oxazoline moieties is installed in the second step. Finally, a first entry towards catalytic activity is given. In this context, modification of the ligand pattern and steric crowding around the central pyridine ring is examined and led to modest to fair ee's in the construction of binaphthyl substrates.
Biomimetic aryl hydroxylation derived from alkyl hydroperoxide at a nonheme iron center. Evidence for an FeIV=O oxidant
Jensen, Michael P.,Lange, Steven J.,Mehn, Mark P.,Que, Emily L.,Que Jr., Lawrence
, p. 2113 - 2128 (2007/10/03)
Many nonheme iron-dependent enzymes activate dioxygen to catalyze hydroxylations of arene substrates. Key features of this chemistry have been developed from complexes of a family of tetradentate tripodal ligands obtained by modification of tris(2-pyridyl
