Cas 503039-60-9,Benzoic acid, 4-[(1,4-dihydro-1-methyl-2,4-dioxo-3(2H)-quinazolinyl)methyl]-

503039-60-9

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Basic information

Product Name: Benzoic acid, 4-[(1,4-dihydro-1-methyl-2,4-dioxo-3(2H)-quinazolinyl)methyl]-
Synonyms:
CAS NO:503039-60-9
Molecular Formula: C17H14N2O4
Molecular Weight: 310.309
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: Benzoic acid, 4-[(1,4-dihydro-1-methyl-2,4-dioxo-3(2H)-quinazolinyl)methyl]-(CAS DataBase Reference)
NIST Chemistry Reference: Benzoic acid, 4-[(1,4-dihydro-1-methyl-2,4-dioxo-3(2H)-quinazolinyl)methyl]-(503039-60-9)
EPA Substance Registry System: Benzoic acid, 4-[(1,4-dihydro-1-methyl-2,4-dioxo-3(2H)-quinazolinyl)methyl]-(503039-60-9)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 503039-60-9(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 503039-60-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,3,0,3 and 9 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 503039-60:
(8*5)+(7*0)+(6*3)+(5*0)+(4*3)+(3*9)+(2*6)+(1*0)=109
109 % 10 = 9
So 503039-60-9 is a valid CAS Registry Number.

503039-60-9Upstream product

503039-60-9Downstream Products

503039-60-9Relevant academic research and scientific papers

N-(2-Amino-phenyl)-4-(heteroarylmethyl)-benzamides as new histone deacetylase inhibitors

Vaisburg, Arkadii,Paquin, Isabelle,Bernstein, Naomy,Frechette, Sylvie,Gaudette, Frederic,Leit, Silvana,Moradei, Oscar,Raeppel, Stephane,Zhou, Nancy,Bouchain, Giliane,Woo, Soon Hyung,Jin, Zhiyun,Gillespie, Jeff,Wang, James,Fournel, Marielle,Yan, Pu Theresa,Trachy-Bourget, Marie-Claude,Robert, Marie-France,Lu, Aihua,Yuk, Jimmy,Rahil, Jubrail,MacLeod, A. Robert,Besterman, Jeffrey M.,Li, Zuomei,Delorme, Daniel

, p. 6729 - 6733 (2007)

A variety of N-(2-amino-phenyl)-4-(heteroarylmethyl)-benzamides were designed and synthesized. These compounds were shown to inhibit recombinant human HDAC1 with IC50 values in the sub-micromolar range. In human cancer cells growing in culture these compounds induced hyperacetylation of histones, induced the expression of the tumor suppressor protein p21WAF1/Cip1, and inhibited cellular proliferation. Certain compounds of this class also showed in vivo activity in various human tumor xenograft models in mice.

Inhibitors of histone deacetylase

-

, (2008/06/13)

The invention relates to the inhibition of histone deacetylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.

Inhibitors of histone deacetylase

-

, (2008/06/13)

Inhibitors of histone deacetylase

-

, (2008/06/13)

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