503071-74-7

Basic information

• Product Name: 2-(4-fluorophenyl)-3-(2-methylsulfanylpyrimidin-4-yl)-6,7-dihydro-5H-pyrazolo[1,2-a]pyrazol-1-one
• Synonyms: 2-(4-fluorophenyl)-3-(2-methylsulfanylpyrimidin-4-yl)-6,7-dihydro-5H-pyrazolo[1,2-a]pyrazol-1-one
• CAS NO: 503071-74-7
• Molecular Weight: 342.397
• Mol File: 503071-74-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(4-fluorophenyl)-3-(2-methylsulfanylpyrimidin-4-yl)-6,7-dihydro-5H-pyrazolo[1,2-a]pyrazol-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-fluorophenyl)-3-(2-methylsulfanylpyrimidin-4-yl)-6,7-dihydro-5H-pyrazolo[1,2-a]pyrazol-1-one(503071-74-7)
• EPA Substance Registry System: 2-(4-fluorophenyl)-3-(2-methylsulfanylpyrimidin-4-yl)-6,7-dihydro-5H-pyrazolo[1,2-a]pyrazol-1-one(503071-74-7)

Safety Data

• Hazardous Substances Data: 503071-74-7(Hazardous Substances Data)

Upstream product

• 503177-82-0 2-(methylsulfanyl)pyrimidine-4-carbonyl chloride 
• 1126-44-9 2-methylsulfanylpyrimidine-4-carboxylic acid 
• 503071-70-3 2-(4-fluorophenyl)-3-hydroxy-3-(2-methylsulfanyl-pyrimidin-4-yl)-propionic acid methyl ester 
• 745018-19-3 2-[2-(4-fluorophenyl)acetyl]pyrazolidine-1-carboxylic acid benzyl ester 
• 702695-15-6 2-(4-fluorophenyl)-1-(1-pyrazolidin-1-yl)ethanone 
• 1074-68-6 4-formyl-2-(methylthio)pyrimidine 
• 34837-84-8 4-fluorobenzeneacetic acid methyl ester 
• 89990-54-5 pyrazolidine dihydrogen chloride 
• 503071-67-8 2-(4-fluorophenyl)-3-oxo-3-(2-methylsulfanyl-pyrimidin-4-yl)-propionic acid methyl ester 
• 745018-23-9 2-(4-fluoro-phenyl)-1-[2-(2-methylsulfanyl-pyrimidine-4-carbonyl)-pyrazolidin-1-yl]-ethanone 

Downstream Products

• 503071-72-5 2-(4-fluorophenyl)-3-(2-methanesulfonyl-pyrimidin-4-yl)-6,7-dihydro-5H-pyrazolo[1,2-a]pyrazol-1-one 

Relevant articles and documents

Convergent synthesis of 2,3-bisarylpyrazolones through cyclization of bisacylated pyrazolidines and hydrazines

Cyclization of various bisacylated hydrazines and pyrazolidines using DBU or sodium hydride leads to the formation of various mono-, bi- and tricyclic pyrazolone scaffolds in 41-98% yield. The convergent nature by which the precyclization intermediates are constructed allows for rapid derivatization about the pyrazolone core.